Rythmol and Losartan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rythmol (propafenone hydrochloride) and Losartan (losartan potassium). Common drug interactions include haematoma among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Rythmol and Losartan. It is created by eHealthMe based on reports of 62 people who take the same drugs from the FDA, and is updated regularly.

What is Rythmol?

Rythmol has active ingredients of propafenone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 3,638 Rythmol users. Check the latest studies of Rythmol.

What is Losartan?

Losartan has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 177,695 Losartan users. Check the latest studies of Losartan.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 03, 2026

62 people who take Rythmol and Losartan together, and have interactions are studied.

What are the common drug interactions of Rythmol and Losartan, by gender? *:

female:

Haematoma (collection of blood outside the blood vessels)
Haemorrhage (bleeding)
Heart rate increased
Hypoaesthesia (reduced sense of touch or sensation)
Idiopathic intracranial hypertension (elevated cerebrospinal fluid pressure of unknown cause)
Ill-defined disorder
Infarction (obstruction of the blood supply to an organ or region of tissue)
Infection
Injection site erythema (redness at injection site)
Injection site hypertrophy (enlargement of an organ or tissue from the increase in size of its cells at injection site)

male:

Diarrhoea
Dizziness
Abdominal discomfort
Ageusia (loss of taste functions of the tongue)
Balance disorder
Blood glucose increased
Constipation
Decreased appetite
Dehydration (dryness resulting from the removal of water)
Diverticulum intestinal haemorrhagic (a pouch that is attached to the first part of the small intestine with bleeding)

What are the common drug interactions of Rythmol and Losartan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Benign intracranial hypertension (benign intracranial hypertension (bih) is a headache syndrome)
Idiopathic intracranial hypertension (elevated cerebrospinal fluid pressure of unknown cause)

40-49:

Chronic kidney disease
Renal disorder (kidney disease)
Renal failure (kidney dysfunction)
Renal injury (kidney injury)

50-59:

Injection site reaction
Injection site swelling
Injection site warmth
Labyrinthitis (inflammation of the labyrinth or inner ear)
Nasopharyngitis (inflammation of the nasopharynx)
Nervousness
Pain
Skin exfoliation (removal of the oldest dead skin cells)
Skin ulcer
Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)

60+:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Diarrhoea
Cough
Angina pectoris (chest pain due to ischemia of the heart muscle)
Asthenia (weakness)
Blood urine present
Chest pain
Contusion (a type of hematoma of tissue in which capillaries)
Drug ineffective
Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 9 people, 14.52%
Immunodeficiency Common Variable: 8 people, 12.90%
High Blood Cholesterol: 8 people, 12.90%
Arrhythmias (irregular heartbeat): 8 people, 12.90%
Multiple Myeloma (cancer of the plasma cells): 6 people, 9.68%
Sleep Disorder: 5 people, 8.06%
Psoriasis (immune-mediated disease that affects the skin): 5 people, 8.06%
Cardiac Disorder: 5 people, 8.06%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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