Rythmol and Wellbutrin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rythmol (propafenone hydrochloride) and Wellbutrin (bupropion hydrochloride). Common drug interactions include myocardial infarction among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Rythmol and Wellbutrin. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Rythmol?

Rythmol has active ingredients of propafenone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 3,638 Rythmol users. Check the latest studies of Rythmol.

What is Wellbutrin?

Wellbutrin has active ingredients of bupropion hydrochloride. It is often used in depression. eHealthMe is studying from 117,115 Wellbutrin users. Check the latest studies of Wellbutrin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

32 people who take Rythmol and Wellbutrin together, and have interactions are studied.

Rythmol and Wellbutrin drug interactions.

What are the common drug interactions of Rythmol and Wellbutrin, by gender? *:

female:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nasopharyngitis (inflammation of the nasopharynx)
Nausea (feeling of having an urge to vomit)
Nervous system disorder (a general class of medical conditions affecting the nervous system)
Nervousness
Neuropathy peripheral (surface nerve damage)
Oesophageal candidiasis (fungal infection of oesophagus)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Pain
Platelet count decreased

male:

Chronic kidney disease
Constipation
Aortic disorder
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Back injury
Back pain
Bile duct obstruction (blockage in the tubes that carry bile from the liver to the gallbladder)
Body temperature decreased
Bone disorder
Cardiovascular disorder (heart diseases)

What are the common drug interactions of Rythmol and Wellbutrin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Dizziness
Confusional state
Heart rate increased
Cardioversion
Agitation (state of anxiety or nervous excitement)
Disturbance in attention
Emotional disorder
Feeling jittery
Hyperhidrosis (abnormally increased sweating)
Insomnia (sleeplessness)

50-59:

Fall
Abdominal pain upper
Ankle fracture
Cardiovascular disorder (heart diseases)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Death
Dizziness
Fibula fracture
Heart rate increased
Impaired work ability

60+:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Dizziness
Drug effect decreased
Drug hypersensitivity
Fatigue (feeling of tiredness)
Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Oesophageal candidiasis (fungal infection of oesophagus)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)

What are the existing conditions these people have? *

Pain: 5 people, 15.62%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 12.50%
Infection: 3 people, 9.38%
High Blood Pressure: 3 people, 9.38%
Asthma: 3 people, 9.38%
Constipation: 3 people, 9.38%
Nausea (feeling of having an urge to vomit): 3 people, 9.38%
Cor Pulmonale Chronic (long lasting enlargement of the right ventricle of the heart): 3 people, 9.38%
Stress And Anxiety: 3 people, 9.38%
High Blood Cholesterol: 3 people, 9.38%

* Approximation only. Some reports may have incomplete information.

Do you take Rythmol and Wellbutrin?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously