Salagen and Botox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Salagen (pilocarpine hydrochloride) and Botox (botulinum toxin type a). Common drug interactions include malaise among females.

The phase IV clinical study analyzes what interactions people have when they take Salagen and Botox. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Salagen?

Salagen has active ingredients of pilocarpine hydrochloride. It is often used in sjogren syndrome. eHealthMe is studying from 1,966 Salagen users. Check the latest studies of Salagen.

What is Botox?

Botox has active ingredients of botulinum toxin type a. It is often used in migraine. eHealthMe is studying from 70,513 Botox users. Check the latest studies of Botox.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

22 people who take Salagen and Botox together, and have interactions are studied.

What are the common drug interactions of Salagen and Botox, by gender? *:

female:

Malaise (a feeling of general discomfort or uneasiness)
Arthralgia (joint pain)
Myalgia (muscle pain)
Osteoporosis (bones weak and more likely to break)
Pneumonia
Colitis (inflammation of colon)
Diarrhoea
Insomnia (sleeplessness)
Myositis (inflammation of the muscles)
Pain

male:

n/a

What are the common drug interactions of Salagen and Botox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Colitis (inflammation of colon)
Diarrhoea

50-59:

Malaise (a feeling of general discomfort or uneasiness)
Myositis (inflammation of the muscles)
Pain

60+:

Arthralgia (joint pain)
Bicytopenia (two parameters from the full blood count are low, the term bicytopenia can be used)
Myalgia (muscle pain)
Osteoporosis (bones weak and more likely to break)
Pneumonia
Bronchial wall thickening
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
Calcification of muscle (calcium accumulation in muscle)
Dysphagia (a condition in which swallowing is difficult or painful)
Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

Pain: 6 people, 27.27%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 5 people, 22.73%
Depression: 5 people, 22.73%
Spasmodic Dysphonia (a voice disorder characterized by involuntary movements or spasms of one or more muscles of the larynx): 3 people, 13.64%
Immunodeficiency Common Variable: 3 people, 13.64%

* Approximation only. Some reports may have incomplete information.

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