Salonpas and Synthroid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Salonpas (menthol; methyl salicylate) and Synthroid (levothyroxine sodium). Common drug interactions include drug ineffective among females and benign prostatic hyperplasia among males.

The phase IV clinical study analyzes what interactions people have when they take Salonpas and Synthroid. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Salonpas?

Salonpas has active ingredients of menthol; methyl salicylate. eHealthMe is studying from 630 Salonpas users. Check the latest studies of Salonpas.

What is Synthroid?

Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 249,198 Synthroid users. Check the latest studies of Synthroid.



On Jul, 27, 2026

14 people who take Salonpas and Synthroid together, and have interactions are studied.

Salonpas and Synthroid drug interactions.

What are the common drug interactions of Salonpas and Synthroid, by gender? *:

female:

  1. Drug ineffective
  2. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  3. Application site pain
  4. Application site pruritus (application site severe itching of the skin)
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  6. Death
  7. Dehydration (dryness resulting from the removal of water)
  8. Hyperhidrosis (abnormally increased sweating)
  9. Infusion site extravasation (flow of (blood or lymph) from infusion site)
  10. Infusion site haemorrhage (bleeding from infusion site)

male:

  1. Benign prostatic hyperplasia (benign enlargement of the prostate)
  2. Cardiac failure congestive
  3. Dehydration (dryness resulting from the removal of water)
  4. Dyspnoea (difficult or laboured respiration)
  5. Pneumonia
  6. Squamous cell carcinoma (a cancer of a kind of epithelial cell)

What are the common drug interactions of Salonpas and Synthroid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Drug ineffective

50-59:

n/a

60+:

  1. Application site rash
  2. Dehydration (dryness resulting from the removal of water)
  3. Nausea (feeling of having an urge to vomit)
  4. Pneumonia
  5. Skin discolouration (change of skin colour)
  6. Skin ulcer
  7. Squamous cell carcinoma (a cancer of a kind of epithelial cell)
  8. Vagus nerve disorder
  9. Application site pain
  10. Application site pruritus (application site severe itching of the skin)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 21.43%
  2. Multiple Myeloma (cancer of the plasma cells): 2 people, 14.29%
  3. Immunodeficiency Common Variable: 2 people, 14.29%
  4. Thyroid Diseases: 1 person, 7.14%
  5. Sinus Congestion (blockage of sinus): 1 person, 7.14%
  6. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.14%
  7. Prostate Cancer: 1 person, 7.14%
  8. Prolactinoma (benign tumour (adenoma) of the pituitary gland that produces a hormone called prolactin): 1 person, 7.14%
  9. Pain: 1 person, 7.14%
  10. Musculoskeletal Chest Pain (pain in chest muscle or nerve or bones): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Salonpas and Synthroid?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Salonpas and Synthroid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Salonpas:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Synthroid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Salonpas and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Synthroid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on menthol; methyl salicylate and levothyroxine sodium (the active ingredients of Salonpas and Synthroid, respectively), and Salonpas and Synthroid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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