Sandimmune and Vitamin e drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sandimmune (cyclosporine) and Vitamin e (tocopherols and tocotrienols). Common drug interactions include arthralgia among females and muscle spasms among males.

The phase IV clinical study analyzes what interactions people have when they take Sandimmune and Vitamin e. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Sandimmune?

Sandimmune has active ingredients of cyclosporine. eHealthMe is studying from 6,694 Sandimmune users. Check the latest studies of Sandimmune.

What is Vitamin e?

Vitamin e has active ingredients of tocopherols and tocotrienols. It is often used in vitamin supplementation. eHealthMe is studying from 42,279 Vitamin e users. Check the latest studies of Vitamin e.

On Aug, 02, 2026

17 people who take Sandimmune and Vitamin e together, and have interactions are studied.

Sandimmune and Vitamin e drug interactions.

What are the common drug interactions of Sandimmune and Vitamin E, by gender? *:

female:

Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Cellulitis (infection under the skin)
Gouty arthritis (joint inflammation with crystal formation)
Graft rejection (graft failure)
Joint stiffness
Joint swelling
Rash erythematous (redness of the skin)
Abdominal pain
Atrioventricular block complete (heart block complete)

male:

Muscle spasms (muscle contraction)
Blindness
Blood creatine phosphokinase increased
Blood creatinine increased
C-reactive protein increased
Conjunctivitis (pink eye)
Epidermal necrolysis (skin condition that is usually caused by a reaction to drugs)
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
International normalised ratio increased
Multi-organ failure (multisystem organ failure)

What are the common drug interactions of Sandimmune and Vitamin E, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Cerebral infarction (less blood supply to brain resulting tissue damage)
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Hemiplegia (paralysis of one side of the body)
Hypoaesthesia (reduced sense of touch or sensation)
Vision blurred

30-39:

n/a

40-49:

Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
C-reactive protein increased
Conjunctivitis (pink eye)
Epidermal necrolysis (skin condition that is usually caused by a reaction to drugs)
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Multi-organ failure (multisystem organ failure)
Pneumonia
Rash erythematous (redness of the skin)
Rash macular (small, flat red spots)
Sarcoma (rare cancers that develop in the muscle, bone, nerves, cartilage, tendons, blood vessels and the fatty and fibrous tissues)

50-59:

Graft rejection (graft failure)
Asthenia (weakness)
Blood creatine phosphokinase increased
Blood creatinine increased
Hepatitis c
Muscle spasms (muscle contraction)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Renal impairment (severely reduced kidney function)
Weight increased

60+:

Blindness
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Cellulitis (infection under the skin)
Gouty arthritis (joint inflammation with crystal formation)
Joint stiffness
Joint swelling
Rash erythematous (redness of the skin)
Abdominal pain
Atrioventricular block complete (heart block complete)
Blood uric acid increased

What are the existing conditions these people have? *

Lipids Increased (excess lipid in body): 3 people, 17.65%
High Blood Cholesterol: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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