Sandostatin and Augmentin '125' drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sandostatin (octreotide acetate) and Augmentin '125' (amoxicillin; clavulanate potassium). Common drug interactions include blood pressure increased among females and coma among males.

The phase IV clinical study analyzes what interactions people have when they take Sandostatin and Augmentin '125'. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Sandostatin?

Sandostatin has active ingredients of octreotide acetate. It is often used in acromegaly. eHealthMe is studying from 46,793 Sandostatin users. Check the latest studies of Sandostatin.

What is Augmentin '125'?

Augmentin '125' has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 10,452 Augmentin '125' users. Check the latest studies of Augmentin '125'.



On Jul, 15, 2026

22 people who take Sandostatin and Augmentin '125' together, and have interactions are studied.

Sandostatin and Augmentin '125' drug interactions.

What are the common drug interactions of Sandostatin and Augmentin '125', by gender? *:

female:

  1. Blood pressure increased
  2. Cough
  3. Gastrointestinal viral infection (virus infection of gastrointestinal tract)
  4. Influenza
  5. Lung infection
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  8. Rhinorrhoea (watery mucus discharge from the nose)
  9. Depression
  10. Nervousness

male:

  1. Coma (state of unconsciousness lasting more than six hours)
  2. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
  3. Abdominal pain
  4. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  5. Blood creatine phosphokinase increased
  6. Blood myoglobin increased
  7. Diarrhoea
  8. Drug toxicity
  9. Erosive oesophagitis (acid reflux disease can cause tissue damage in the oesophagus over time)
  10. Haematemesis (vomiting of blood)

What are the common drug interactions of Sandostatin and Augmentin '125', by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Blood pressure increased
  2. Cough
  3. Gastrointestinal viral infection (virus infection of gastrointestinal tract)
  4. Influenza
  5. Lung infection
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  8. Rhinorrhoea (watery mucus discharge from the nose)
  9. Depression
  10. Nervousness

30-39:

n/a

40-49:

  1. Alanine aminotransferase increased
  2. Blood alkaline phosphatase increased
  3. Colon cancer
  4. Hyperbilirubinaemia (excess of bilirubin in the blood)
  5. Small intestine carcinoma (cancer tumour of small intestine)

50-59:

  1. Coma (state of unconsciousness lasting more than six hours)
  2. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
  3. Epistaxis (bleed from the nose)
  4. Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
  5. Septic shock (shock due to blood infection)
  6. Lung disorder (lung disease)
  7. Acute myocardial infarction (acute heart attack)
  8. Blood pressure systolic increased
  9. Fatigue (feeling of tiredness)
  10. Haemoglobin decreased

60+:

  1. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  2. Blood pressure decreased
  3. Erosive oesophagitis (acid reflux disease can cause tissue damage in the oesophagus over time)
  4. Hepatic failure (liver failure)
  5. Mucosal erosion (peeling off of mucous membrane)
  6. Ocular hyperaemia (an abnormally large amount of blood in eye)
  7. Pyrexia (fever)
  8. Sepsis (a severe blood infection that can lead to organ failure and death)
  9. Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
  10. Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)

What are the existing conditions these people have? *

  1. Upper Gastrointestinal Haemorrhage (upper gastrointestinal bleeding): 5 people, 22.73%
  2. High Blood Pressure: 4 people, 18.18%
  3. Pain: 4 people, 18.18%
  4. Diarrhea: 3 people, 13.64%
  5. Headache (pain in head): 3 people, 13.64%
  6. Indigestion: 3 people, 13.64%
  7. Insomnia (sleeplessness): 3 people, 13.64%
  8. Oedema Peripheral (superficial swelling): 3 people, 13.64%
  9. Nausea (feeling of having an urge to vomit): 3 people, 13.64%
  10. Constipation: 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Sandostatin and Augmentin '125':

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Sandostatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Augmentin '125':

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sandostatin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Augmentin '125' and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on octreotide acetate and amoxicillin; clavulanate potassium (the active ingredients of Sandostatin and Augmentin '125', respectively), and Sandostatin and Augmentin '125' (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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