Saphris and Crestor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Saphris (asenapine maleate) and Crestor (rosuvastatin calcium). Common drug interactions include diabetes mellitus among females and depression among males.

The phase IV clinical study analyzes what interactions people have when they take Saphris and Crestor. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.

What is Saphris?

Saphris has active ingredients of asenapine maleate. It is often used in bipolar i disorder. eHealthMe is studying from 8,688 Saphris users. Check the latest studies of Saphris.

What is Crestor?

Crestor has active ingredients of rosuvastatin calcium. It is often used in high blood cholesterol. eHealthMe is studying from 149,761 Crestor users. Check the latest studies of Crestor.

On Jul, 26, 2026

59 people who take Saphris and Crestor together, and have interactions are studied.

What are the common drug interactions of Saphris and Crestor, by gender? *:

female:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dizziness
Drug ineffective
Dysgeusia (disorder of the sense of taste)
Ear infection
Feeling drunk
Haemorrhage (bleeding)
Headache (pain in head)
Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
Hypomania (a mild form of mania, marked by elation and hyperactivity)

male:

Depression
Agitation (state of anxiety or nervous excitement)
Abnormal dreams
Bone density decreased
Delusion (a false belief or opinion)
Migraine (headache)
Osteoporosis (bones weak and more likely to break)
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Blood pressure increased

What are the common drug interactions of Saphris and Crestor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anaphylactic reaction (serious allergic reaction)
Brachial plexus injury (brachial plexus injuries, are caused by damage to those nerves network that conducts signals from the spinal cord)
Migraine (headache)
Thyroid disorder (thyroid diseases)

30-39:

Therapeutic response unexpected
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Fall
Hunger
Ill-defined disorder
Intervertebral disc protrusion (spinal disc protrusion)
Oral disorder (mouth disease)
Spinal column injury (spinal cord bone injury)
Vitamin d deficiency
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)

40-49:

Hepatitis b
Thrombocytopenia (decrease of platelets in blood)
Body temperature decreased
Chronic kidney disease
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
Malaise (a feeling of general discomfort or uneasiness)
Muscle spasms (muscle contraction)
Muscle twitching
Nasopharyngitis (inflammation of the nasopharynx)

50-59:

Depression
Weight increased
Tardive dyskinesia (a disorder that involves involuntary movements)
Anaphylactic reaction (serious allergic reaction)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Contusion (a type of hematoma of tissue in which capillaries)
Crying
Disturbance in attention
Dyspnoea (difficult or laboured respiration)
Dysuria (painful or difficult urination)

60+:

Blood pressure increased
Ear infection
Headache (pain in head)
Oedema peripheral (superficial swelling)
Sinus congestion (blockage of sinus)
Sinusitis (inflammation of sinus)
Tardive dyskinesia (a disorder that involves involuntary movements)
Tremor (trembling or shaking movements in one or more parts of your body)
Vertigo

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 22 people, 37.29%
Depression: 9 people, 15.25%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 13.56%
Bipolar Disorder (mood disorder): 6 people, 10.17%
Hiv Infection: 5 people, 8.47%
Pain: 4 people, 6.78%
High Blood Pressure: 4 people, 6.78%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 6.78%
Stress And Anxiety: 3 people, 5.08%
Sleep Disorder: 3 people, 5.08%

* Approximation only. Some reports may have incomplete information.

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