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Saphris and Prevacid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Saphris (asenapine maleate) and Prevacid (lansoprazole). Common drug interactions include blister among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Saphris and Prevacid. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Saphris?

Saphris has active ingredients of asenapine maleate. It is often used in bipolar i disorder. eHealthMe is studying from 8,688 Saphris users. Check the latest studies of Saphris.

What is Prevacid?

Prevacid has active ingredients of lansoprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 130,714 Prevacid users. Check the latest studies of Prevacid.

On Jul, 20, 2026

24 people who take Saphris and Prevacid together, and have interactions are studied.

Saphris and Prevacid drug interactions.

What are the common drug interactions of Saphris and Prevacid, by gender? *:

female:

  1. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  2. Chronic kidney disease
  3. Ear disorder
  4. Nephrogenic anaemia (anaemia due to kidney disease)
  5. Panic attack
  6. Renal failure (kidney dysfunction)
  7. Agitation (state of anxiety or nervous excitement)
  8. Depression
  9. Drug ineffective
  10. Dyspnoea (difficult or laboured respiration)

male:

  1. Chronic kidney disease
  2. Insomnia (sleeplessness)
  3. Suicidal ideation
  4. Akathisia (a movement disorder characterized by a feeling of inner restlessness)
  5. Angioedema (rapid swelling of the dermis)
  6. Asthenia (weakness)
  7. Back pain
  8. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  9. Cat scratch disease (bacterial infection by cat scratch)
  10. Coma (state of unconsciousness lasting more than six hours)

What are the common drug interactions of Saphris and Prevacid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Akathisia (a movement disorder characterized by a feeling of inner restlessness)
  2. Angioedema (rapid swelling of the dermis)
  3. Back pain
  4. Cat scratch disease (bacterial infection by cat scratch)
  5. Coma (state of unconsciousness lasting more than six hours)
  6. Constipation
  7. Cyclic vomiting syndrome (prolonged episodes of severe nausea, vomiting)
  8. Drug ineffective
  9. Dyskinesia (abnormality or impairment of voluntary movement)
  10. Flushing (the warm, red condition of human skin)

30-39:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Asthenia (weakness)
  4. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  5. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  6. Drooling (drop saliva uncontrollably from the mouth)
  7. Fatigue (feeling of tiredness)
  8. Herpes zoster
  9. Lower respiratory tract infection
  10. Nausea (feeling of having an urge to vomit)

40-49:

  1. Chronic kidney disease
  2. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  3. Ear disorder
  4. Nephrogenic anaemia (anaemia due to kidney disease)
  5. Panic attack
  6. Renal failure (kidney dysfunction)
  7. Agitation (state of anxiety or nervous excitement)
  8. Depression
  9. Drug ineffective
  10. Inappropriate affect

50-59:

  1. Dyspnoea (difficult or laboured respiration)
  2. Irritability
  3. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  4. Renal failure (kidney dysfunction)
  5. Renal injury (kidney injury)
  6. Somnolence (a state of near-sleep, a strong desire for sleep)
  7. Suicidal ideation
  8. Toothache (tooth pain)
  9. Arthralgia (joint pain)
  10. Chronic kidney disease

60+:

  1. Road traffic accident

What are the existing conditions these people have? *

  1. High Blood Cholesterol: 4 people, 16.67%
  2. Depression: 4 people, 16.67%
  3. High Blood Pressure: 4 people, 16.67%
  4. Bipolar Disorder (mood disorder): 3 people, 12.50%
  5. Urticaria (rash of round, red welts on the skin that itch intensely): 2 people, 8.33%
  6. Inflammation: 2 people, 8.33%
  7. Infection: 2 people, 8.33%
  8. Indigestion: 2 people, 8.33%
  9. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 8.33%
  10. Hypersensitivity: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Saphris and Prevacid?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Saphris and Prevacid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Saphris:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Prevacid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Saphris and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prevacid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on asenapine maleate and lansoprazole (the active ingredients of Saphris and Prevacid, respectively), and Saphris and Prevacid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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