Hysingla and Peripheral swelling - a phase IV clinical study of FDA data

Summary:

Peripheral swelling is reported as a side effect among people who take Hysingla (hydrocodone bitartrate), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Albuterol, and have Immunodeficiency common variable.

The phase IV clinical study analyzes which people have Peripheral swelling when taking Hysingla. It is created by eHealthMe based on reports of 32,589 people who have side effects when taking Hysingla from the FDA, and is updated regularly.

What is Hysingla?

Hysingla has active ingredients of hydrocodone bitartrate. eHealthMe is studying from 32,609 Hysingla users. Check the latest studies of Hysingla.

What is Peripheral swelling?

Peripheral swelling is found to be associated with 2,180 drugs and 1,741 conditions by eHealthMe. Check the latest studies of Peripheral swelling.

On Jul, 20, 2026

32,589 people reported to have side effects when taking Hysingla.
Among them, 21 people (0.06%) have Peripheral swelling.

Could Hysingla cause Peripheral swelling?

Among these 21 people:

How long have people been on Hysingla when they have Peripheral swelling? *

What is the gender of people who have Peripheral swelling when taking Hysingla? *

female: 71.43 %
male: 28.57 %

What is the age of people who have Peripheral swelling when taking Hysingla? *

What are other drugs people take besides Hysingla? *

What are other side effects people have besides Peripheral swelling? *

Cellulitis (infection under the skin): 4 people, 19.05%
Weight Increased: 3 people, 14.29%
Abscess (pus): 3 people, 14.29%
Stress And Anxiety: 2 people, 9.52%
Neck Pain: 2 people, 9.52%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 2 people, 9.52%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 2 people, 9.52%
Rashes (redness): 2 people, 9.52%
Muscle Aches (muscle pain): 2 people, 9.52%
Drug Dependence: 2 people, 9.52%

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 4 people, 19.05%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 1 person, 4.76%
Pain: 1 person, 4.76%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1 person, 4.76%
Muscle Strain (an injury to a muscle in which the muscle fibres tear): 1 person, 4.76%
Muscle Spasms (muscle contraction): 1 person, 4.76%
Iron Deficiency Anaemia: 1 person, 4.76%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 4.76%
Back Pain: 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Hysingla and have Peripheral swelling?

- Check whether Peripheral swelling is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hysingla:

Hysingla (32,609 reports)

Browse all side effects of Hysingla:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Peripheral swelling:

Peripheral swelling (2,180 drugs)

Browse all the conditions that are associated with Peripheral swelling:

Peripheral swelling (1,741 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrocodone bitartrate (the active ingredients of Hysingla) and Hysingla (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.