Savella and Alcohol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Savella (milnacipran hydrochloride) and Alcohol (alcohol). Common drug interactions include cholangitis among females and agitation among males.

The phase IV clinical study analyzes what interactions people have when they take Savella and Alcohol. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Savella?

Savella has active ingredients of milnacipran hydrochloride. It is often used in fibromyalgia. eHealthMe is studying from 7,529 Savella users. Check the latest studies of Savella.

What is Alcohol?

Alcohol has active ingredients of alcohol. It is often used in stress and anxiety. eHealthMe is studying from 23,388 Alcohol users. Check the latest studies of Alcohol.

On Aug, 09, 2026

15 people who take Savella and Alcohol together, and have interactions are studied.

What are the common drug interactions of Savella and Alcohol, by gender? *:

female:

Cholangitis (infection of the bile duct)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Headache (pain in head)
Neuralgia (pain in one or more nerves)
Blood potassium decreased
Cardiac arrest
Coma (state of unconsciousness lasting more than six hours)
Diarrhoea
Drug screen positive
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)

male:

Agitation (state of anxiety or nervous excitement)
Insomnia (sleeplessness)
Nervousness
Suicidal ideation
Suicide attempt

What are the common drug interactions of Savella and Alcohol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Suicide attempt
Suicidal ideation
Mood swings (an extreme or rapid change in mood)
Multiple drug overdose intentional
Agitation (state of anxiety or nervous excitement)
Insomnia (sleeplessness)
Nervousness
Near drowning (means a person almost died from not being able to breathe under water)
Alopecia (absence of hair from areas of the body)
Cholangitis (infection of the bile duct)

60+:

Blood potassium decreased
Cardiac arrest
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Vomiting
Weight decreased
Suicide attempt
Drug hypersensitivity
Coma (state of unconsciousness lasting more than six hours)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 40.00%
Drowsiness: 4 people, 26.67%
Insomnia (sleeplessness): 3 people, 20.00%
Hypersensitivity: 3 people, 20.00%
Pain: 2 people, 13.33%
Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 2 people, 13.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 13.33%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 13.33%
Back Pain: 2 people, 13.33%
Seasonal Allergy (allergic condition due to certain season): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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