Sectral and Tranxene drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sectral (acebutolol hydrochloride) and Tranxene (clorazepate dipotassium). Common drug interactions include hallucination among females and fall among males.

The phase IV clinical study analyzes what interactions people have when they take Sectral and Tranxene. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Sectral?

Sectral has active ingredients of acebutolol hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 3,548 Sectral users. Check the latest studies of Sectral.

What is Tranxene?

Tranxene has active ingredients of clorazepate dipotassium. It is often used in stress and anxiety. eHealthMe is studying from 6,550 Tranxene users. Check the latest studies of Tranxene.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

27 people who take Sectral and Tranxene together, and have interactions are studied.

What are the common drug interactions of Sectral and Tranxene, by gender? *:

female:

Hallucination (an experience involving the perception of something not present)
Heart injury
Hypovolaemia (a decreased volume of circulating blood in the body)
Injury
International normalised ratio decreased
Laboratory test abnormal
Left ventricular dysfunction
Lung infection
Mitral valve incompetence (inefficient heart valve)
Mobility decreased (ability to move is reduced)

male:

Fall
Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Iiird nerve paralysis (totally closed eyelid and a down and out deviation of the eye)
Oedema (fluid collection in tissue)
Overdose
Paraparesis (partial paralysis of the lower limbs)
Pruritus generalised (generalized itching)
Rash macular (small, flat red spots)
Red blood cell sedimentation rate increased
Serum ferritin increased

What are the common drug interactions of Sectral and Tranxene, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Pyrexia (fever)
Asthenia (weakness)
Chest pain
Electrocardiogram abnormal
Oesophageal spasm (contraction of oesophagus)
Depressed level of consciousness
Dermatitis exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss)
Hypotension (abnormally low blood pressure)
Hypovolaemic shock (shock caused by severe blood or fluid loss)
Laboratory test abnormal

50-59:

Hepatic steatosis (fatty liver disease)
Hypercholesterolaemia (high levels of cholesterol in the blood)
Hypertriglyceridaemia (excess of triglycerides in the blood)
Insulin-requiring type 2 diabetes mellitus
Oedema upper limb (swelling of arm)
Pyoderma gangrenosum (ulcerating condition of skin that results in heaped borders with a typical appearance)
Red blood cell sedimentation rate increased
Serum ferritin increased
Throat oedema (swelling of throat)
Throat tightness

60+:

Fall
Anaemia (lack of blood)
Melaena (the passage of black, tarry stools)
Mouth injury
Oedema (fluid collection in tissue)
Pruritus generalised (generalized itching)
Rash macular (small, flat red spots)
Renal failure acute (rapid kidney dysfunction)
Skin exfoliation (removal of the oldest dead skin cells)
Tooth disorder (tooth disease)

What are the existing conditions these people have? *

Bipolar Disorder (mood disorder): 5 people, 18.52%
Neuralgia (pain in one or more nerves): 2 people, 7.41%
Heart Attack: 2 people, 7.41%
Essential Hypertension (primary hypertension): 2 people, 7.41%
Angina Unstable (chest pain due to ischemia of the heart muscle- unstable): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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