Senna and Misoprostol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Senna (senna) and Misoprostol (misoprostol). Common drug interactions include bronchitis among females and sleep apnoea syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Senna and Misoprostol. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.

What is Senna?

Senna has active ingredients of senna. It is often used in constipation. eHealthMe is studying from 37,302 Senna users. Check the latest studies of Senna.

What is Misoprostol?

Misoprostol has active ingredients of misoprostol. It is often used in abortion. eHealthMe is studying from 8,222 Misoprostol users. Check the latest studies of Misoprostol.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

43 people who take Senna and Misoprostol together, and have interactions are studied.

Senna and Misoprostol drug interactions.

What are the common drug interactions of Senna and Misoprostol, by gender? *:

female:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Contusion (a type of hematoma of tissue in which capillaries)
Decreased appetite
Dyspnoea (difficult or laboured respiration)
Facial bones fracture (bone fracture of face)
Fall
Fatigue (feeling of tiredness)
Gait disturbance
Hypersomnia (excessive daytime sleepiness (eds))
Injection site erythema (redness at injection site)

male:

Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Arthralgia (joint pain)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Deformity (disfigurement)
Dental caries
Disability
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Haemorrhagic anaemia (anaemia due to excessive bleeding)
Hip fracture
Mitral valve incompetence (inefficient heart valve)

What are the common drug interactions of Senna and Misoprostol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Influenza

20-29:

n/a

30-39:

n/a

40-49:

Alanine aminotransferase increased
Antipsychotic drug level increased
Blood albumin decreased
Blood alkaline phosphatase increased
Gamma-glutamyltransferase increased
Haemoglobin decreased
Lung neoplasm malignant (cancer tumour of lung)
Platelet count increased
Red blood cell count decreased
Total cholesterol/hdl ratio increased

50-59:

Fall
Headache (pain in head)
Injury
Joint injury
Physical assault
Road traffic accident
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Spinal disorder (disease of spine a back bone)
Suicidal ideation
Arrhythmia (irregular heartbeat)

60+:

Fatigue (feeling of tiredness)
Pain
Swelling
Neck pain
Pruritus (severe itching of the skin)
Decreased appetite
Rash
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Facial bones fracture (bone fracture of face)
Fall

What are the existing conditions these people have? *

Pain: 7 people, 16.28%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 6 people, 13.95%
Metastases To Bone (cancer spreads to bone): 5 people, 11.63%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 4 people, 9.30%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 4 people, 9.30%
Asthma: 4 people, 9.30%
Metastases To Prostate (cancer spreads to prostate): 3 people, 6.98%

* Approximation only. Some reports may have incomplete information.

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