Sennosides and Adderall drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sennosides (senna) and Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate). Common drug interactions include dry mouth among females and emergency care among males.

The phase IV clinical study analyzes what interactions people have when they take Sennosides and Adderall. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Sennosides?

Sennosides has active ingredients of senna. It is often used in constipation. eHealthMe is studying from 8,247 Sennosides users. Check the latest studies of Sennosides.

What is Adderall?

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 64,224 Adderall users. Check the latest studies of Adderall.

On Jul, 09, 2026

16 people who take Sennosides and Adderall together, and have interactions are studied.

Sennosides and Adderall drug interactions.

What are the common drug interactions of Sennosides and Adderall, by gender? *:

female:

Dry mouth
Gait disturbance
Muscle spasms (muscle contraction)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Abnormal behaviour
Abnormal dreams
Allergy to animal
Antinuclear antibody positive
Asthenia (weakness)
Asthma

male:

Emergency care
Cardiac infection (an infection of the heart)
Postural orthostatic tachycardia syndrome (abnormal increase in heart rate on becoming upright)
Anxiety
Fall
Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy)
Suicidal ideation
Therapeutic response unexpected
Thrombosis (formation of a blood clot inside a blood vessel)

What are the common drug interactions of Sennosides and Adderall, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Anxiety
Emergency care
Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy)
Suicidal ideation
Therapeutic response unexpected

20-29:

n/a

30-39:

Hemiparesis (weakness on one side of the body)
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Speech disorder

40-49:

Cerebrospinal fluid leakage
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)

50-59:

Death
Dry mouth
Fatigue (feeling of tiredness)
Gait disturbance
Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
Muscular weakness (muscle weakness)
Optic atrophy (the loss of a proportion of optic disc nerve fibres)
Optic neuritis (optic nerve inflammation)
Pain in extremity
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

60+:

Abnormal dreams
Asthenia (weakness)
Injury
Motion sickness (travel sickness)
Muscle spasms (muscle contraction)
Reading disorder (problem in areas of the brain that help interpret language)
Thrombosis (formation of a blood clot inside a blood vessel)
Bedridden
Drug ineffective
Euphoric mood (excessively happy but may become angry or irritable)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 43.75%
Pain: 3 people, 18.75%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 18.75%
Seasonal Allergy (allergic condition due to certain season): 2 people, 12.50%
Pancreatic Carcinoma Metastatic (pancreatic cancer- metastatic): 2 people, 12.50%
Depression: 2 people, 12.50%
Insomnia (sleeplessness): 2 people, 12.50%
Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 2 people, 12.50%
Asthma: 2 people, 12.50%
Nausea (feeling of having an urge to vomit): 2 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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