Septra ds and Seroquel drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Septra ds (sulfamethoxazole; trimethoprim) and Seroquel (quetiapine fumarate). Common drug interactions include convulsion among females and constipation among males.
The phase IV clinical study analyzes what interactions people have when they take Septra ds and Seroquel. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.
What is Septra ds?
Septra ds has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 2,349 Septra ds users. Check the latest studies of Septra ds.
What is Seroquel?
Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 120,285 Seroquel users. Check the latest studies of Seroquel.
32 people who take Septra ds and Seroquel together, and have interactions are studied.

What are the common drug interactions of Septra Ds and Seroquel, by gender? *:
female:
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Cough
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Drug level increased
- Dyspnoea (difficult or laboured respiration)
- Fungal infection
- Gastroenteritis (inflammation of stomach and intestine)
- Haemoglobin decreased
- Hepatic steatosis (fatty liver disease)
- Hypertension (high blood pressure)
male:
- Constipation
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Arrhythmia (irregular heartbeat)
- Arteriosclerosis (thickening and hardening of arteries)
- Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
- Back pain
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Cerebral haemorrhage (bleeding within the brain)
- Dyspepsia (indigestion)
- Fatigue (feeling of tiredness)
What are the common drug interactions of Septra Ds and Seroquel, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Abdominal pain
- Asthenia (weakness)
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
- Coma (state of unconsciousness lasting more than six hours)
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Drug level increased
- Headache (pain in head)
- Hepatic steatosis (fatty liver disease)
- Metabolic disorder (an abnormal function and pattern of body fat. insulin resistance refers to the diminished ability of cells to respond to the action of insulin in promoting the transport of the sugar glucose, from blood into muscles and other tissues)
- Pancreatic necrosis (death of pancreas tissue in pancreas)
30-39:
- Kidney infection
- Anogenital warts
- Blood hiv rna increased
- Renal failure (kidney dysfunction)
- Viral load increased
- Anxiety
- Humerus fracture (injury to the upper arm bone)
- Multiple fractures
- Tooth loss
- Upper limb fracture
40-49:
- Cough
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
- Back pain
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Constipation
- Dyspepsia (indigestion)
- Fatigue (feeling of tiredness)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Haemorrhoids (a swollen vein or group of veins in the region of the anus)
50-59:
- Hypoxia (low oxygen in tissues)
- Post procedural complication
- Sedation
- Wheezing (a high-pitched whistling sound made while you breath)
60+:
- Type 2 diabetes mellitus
- Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
- Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
- Confusional state
- Diabetes mellitus non-insulin-dependent
- Electrocardiogram repolarisation abnormality
- Headache (pain in head)
- Hypotension (abnormally low blood pressure)
- Lipase increased
- Loss of consciousness
What are the existing conditions these people have? *
- Pain: 5 people, 15.62%
- Hiv Infection: 5 people, 15.62%
- Back Pain: 4 people, 12.50%
- Depression: 3 people, 9.38%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 9.38%
- Multiple Myeloma (cancer of the plasma cells): 3 people, 9.38%
- Stress And Anxiety: 2 people, 6.25%
- Hypokalemia (low potassium): 2 people, 6.25%
- Chest Pain: 2 people, 6.25%
- High Blood Cholesterol: 2 people, 6.25%
* Approximation only. Some reports may have incomplete information.
Do you take Septra ds and Seroquel?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Septra ds and Seroquel:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Septra ds:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Seroquel:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Septra ds and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Seroquel and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Mati?, K., & Pele?, A. M. , "Drug-induced toxic hepatitis associated with the combination of quetiapine and fluphenazine: A case report", The European Journal of Psychiatry, 2018 Jan .
- Shah Z, Londhe V, "Influence of various media on the dissolution profiles of immediate-release quetiapine tablets in India", Dissolution Technologies, 2016 Feb .
- Mati?, K., & Pele?, A. M. , "Drug-induced toxic hepatitis associated with the combination of quetiapine and fluphenazine: A case report", The European Journal of Psychiatry, 2018 Jan .
- Shah Z, Londhe V, "Influence of various media on the dissolution profiles of immediate-release quetiapine tablets in India", Dissolution Technologies, 2016 Feb .
How the study uses the data?
The study uses data from the FDA. It is based on sulfamethoxazole; trimethoprim and quetiapine fumarate (the active ingredients of Septra ds and Seroquel, respectively), and Septra ds and Seroquel (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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