Septra and Viracept drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Septra (sulfamethoxazole; trimethoprim) and Viracept (nelfinavir mesylate). Common drug interactions include pancytopenia among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Septra and Viracept. It is created by eHealthMe based on reports of 58 people who take the same drugs from the FDA, and is updated regularly.

What is Septra?

Septra has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 10,280 Septra users. Check the latest studies of Septra.

What is Viracept?

Viracept has active ingredients of nelfinavir mesylate. It is often used in hiv infection. eHealthMe is studying from 6,399 Viracept users. Check the latest studies of Viracept.

On Jul, 26, 2026

58 people who take Septra and Viracept together, and have interactions are studied.

What are the common drug interactions of Septra and Viracept, by gender? *:

female:

Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pregnancy
Abortion induced (medically referred abortion)
Chest pain
Disturbance in attention
Flushing (the warm, red condition of human skin)
Fracture
Haematemesis (vomiting of blood)
Heart rate increased
Insomnia (sleeplessness)

male:

Pyrexia (fever)
Tremor (trembling or shaking movements in one or more parts of your body)
Anger
Anxiety
Aseptic necrosis bone
Aspartate aminotransferase increased
Blood lactate dehydrogenase increased
Confusional state
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)

What are the common drug interactions of Septra and Viracept, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anasarca (general swelling, or massive oedema)
Arrhythmia (irregular heartbeat)
Blood potassium increased
Blood sodium decreased
Cellulitis (infection under the skin)
Coma (state of unconsciousness lasting more than six hours)
Dehydration (dryness resulting from the removal of water)
Electrolyte imbalance
Gastroenteritis (inflammation of stomach and intestine)
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)

30-39:

Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Markedly reduced food intake
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Nausea (feeling of having an urge to vomit)
Oedema lower limb (fluid collection in tissue of lower leg)
Oedema peripheral (superficial swelling)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Ph urine decreased
Pregnancy
Proteinuria present

40-49:

Blood creatinine increased
Abdominal pain
Alanine aminotransferase increased
Aseptic necrosis bone
Aspartate aminotransferase increased
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Pancreatitis (inflammation of pancreas)
Pyrexia (fever)
Sepsis (a severe blood infection that can lead to organ failure and death)
Blood lactate dehydrogenase increased

50-59:

Dysphagia (a condition in which swallowing is difficult or painful)
Fatigue (feeling of tiredness)
Hiv wasting syndrome (aids wasting syndrome occurs when you have aids and lose at least 10% of your body weight -- especially muscle)
Lipoatrophy (localized loss of fat tissue)
Malaise (a feeling of general discomfort or uneasiness)
Myalgia (muscle pain)
Polycythaemia (proportion of blood volume that is occupied by red blood cells increases)
Pruritus (severe itching of the skin)
Pyrexia (fever)
Rash erythematous (redness of the skin)

60+:

Pancreatitis acute (sudden inflammation of pancreas)
Blood amylase increased
Dyspnoea (difficult or laboured respiration)
Palpitations (feelings or sensations that your heart is pounding or racing)
Ventricular extrasystoles (premature cardiac contraction)

What are the existing conditions these people have? *

Insomnia (sleeplessness): 3 people, 5.17%
Depression: 3 people, 5.17%

* Approximation only. Some reports may have incomplete information.

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