Loniten and Reglan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Loniten (minoxidil) and Reglan (metoclopramide hydrochloride). Common drug interactions include blood albumin decreased among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Loniten and Reglan. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Loniten?

Loniten has active ingredients of minoxidil. eHealthMe is studying from 363 Loniten users. Check the latest studies of Loniten.

What is Reglan?

Reglan has active ingredients of metoclopramide hydrochloride. It is often used in gastroparesis. eHealthMe is studying from 29,455 Reglan users. Check the latest studies of Reglan.



On Jul, 26, 2026

21 people who take Loniten and Reglan together, and have interactions are studied.

Loniten and Reglan drug interactions.

What are the common drug interactions of Loniten and Reglan, by gender? *:

female:

  1. Blood albumin decreased
  2. Blood sodium decreased
  3. Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
  4. Deformity (disfigurement)
  5. Diarrhoea
  6. Dysphagia (a condition in which swallowing is difficult or painful)
  7. Dyspnoea (difficult or laboured respiration)
  8. Fall
  9. Fistula (an abnormal connection or passageway between two)
  10. Gastritis (inflammation of stomach)

male:

  1. Anaemia (lack of blood)
  2. Fatigue (feeling of tiredness)
  3. Chronic kidney disease
  4. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  5. Cytomegalovirus colitis (an inflammation of the colon from virus)
  6. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  7. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  8. Diarrhoea
  9. Dizziness
  10. Drug ineffective

What are the common drug interactions of Loniten and Reglan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Gastroenteritis (inflammation of stomach and intestine)
  2. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  3. Pneumonia

30-39:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

40-49:

  1. Arthralgia (joint pain)
  2. Asthenia (weakness)
  3. Chills (felling of cold)
  4. Diarrhoea
  5. Dizziness
  6. Dysgeusia (disorder of the sense of taste)
  7. Dyspnoea (difficult or laboured respiration)
  8. Fatigue (feeling of tiredness)
  9. Feeling cold
  10. Hypertension (high blood pressure)

50-59:

  1. Oedema peripheral (superficial swelling)
  2. Emotional distress
  3. Joint contracture (a permanent shortening of a muscle or joint)
  4. Joint stiffness
  5. Mobility decreased (ability to move is reduced)
  6. Muscular weakness (muscle weakness)
  7. Pain
  8. Pain of skin
  9. Paralysis
  10. Rash macular (small, flat red spots)

60+:

  1. Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

  1. Nuclear Magnetic Resonance Imaging Brain: 12 people, 57.14%
  2. Diabetes: 6 people, 28.57%
  3. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 6 people, 28.57%
  4. Anaemia (lack of blood): 6 people, 28.57%
  5. Pain: 5 people, 23.81%
  6. Chest Pain: 5 people, 23.81%
  7. Haemolytic Uraemic Syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more): 3 people, 14.29%
  8. Stress And Anxiety: 2 people, 9.52%
  9. Nausea And Vomiting: 2 people, 9.52%
  10. Nausea (feeling of having an urge to vomit): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Loniten and Reglan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Loniten:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Reglan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Loniten and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Reglan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on minoxidil and metoclopramide hydrochloride (the active ingredients of Loniten and Reglan, respectively), and Loniten and Reglan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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