Lamictal and Clindamycin hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lamictal (lamotrigine) and Clindamycin hydrochloride (clindamycin hydrochloride). Common drug interactions include depression among females and essential tremor among males.

The phase IV clinical study analyzes what interactions people have when they take Lamictal and Clindamycin hydrochloride. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Lamictal?

Lamictal has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 82,626 Lamictal users. Check the latest studies of Lamictal.

What is Clindamycin hydrochloride?

Clindamycin hydrochloride has active ingredients of clindamycin hydrochloride. It is often used in tooth abscess. eHealthMe is studying from 4,257 Clindamycin hydrochloride users. Check the latest studies of Clindamycin hydrochloride.



On Jul, 26, 2026

14 people who take Lamictal and Clindamycin hydrochloride together, and have interactions are studied.

Lamictal and Clindamycin hydrochloride drug interactions.

What are the common drug interactions of Lamictal and Clindamycin Hydrochloride, by gender? *:

female:

  1. Depression
  2. Hypoaesthesia (reduced sense of touch or sensation)
  3. Hellp syndrome (life-threatening pregnancy complication)
  4. Pre-eclampsia (high blood pressure and significant amounts of protein in the urine of a pregnant woman)
  5. Abdominal pain
  6. Alcohol abuse
  7. Brain injury
  8. Colitis (inflammation of colon)
  9. Completed suicide (act of taking one's own life)
  10. Craniocerebral injury (injury to cranium and brain)

male:

  1. Essential tremor
  2. Speech disorder
  3. Weight decreased

What are the common drug interactions of Lamictal and Clindamycin Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Chest pain
  2. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  3. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  4. Torticollis (a twisted neck in which the head is tipped to one side, while the chin is turned to the other)
  5. Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
  6. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  7. Hellp syndrome (life-threatening pregnancy complication)
  8. Pre-eclampsia (high blood pressure and significant amounts of protein in the urine of a pregnant woman)
  9. Blood pressure increased
  10. Brain injury

40-49:

  1. Psychotic disorder
  2. Suicidal ideation
  3. Suicide attempt
  4. Alcohol abuse
  5. Blood pressure increased
  6. Completed suicide (act of taking one's own life)
  7. Depression
  8. Insomnia (sleeplessness)
  9. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  10. Panic attack

50-59:

  1. Weight decreased

60+:

  1. Essential tremor
  2. Speech disorder

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 11 people, 78.57%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 9 people, 64.29%
  3. Hypersensitivity: 4 people, 28.57%
  4. High Blood Pressure: 3 people, 21.43%
  5. Depression: 3 people, 21.43%
  6. Drowsiness: 3 people, 21.43%
  7. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 3 people, 21.43%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 21.43%
  9. Acne (skin problems that cause pimples): 3 people, 21.43%
  10. Multiple Allergies (allergy to multiple agents): 3 people, 21.43%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lamictal and Clindamycin hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lamictal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Clindamycin hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lamictal and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Clindamycin hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on lamotrigine and clindamycin hydrochloride (the active ingredients of Lamictal and Clindamycin hydrochloride, respectively), and Lamictal and Clindamycin hydrochloride (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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