Seroquel and Arginine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Seroquel (quetiapine fumarate) and Arginine (l - arginine). Common drug interactions include osteoarthritis among females and anxiety among males.
The phase IV clinical study analyzes what interactions people have when they take Seroquel and Arginine. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.
What is Seroquel?
Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 120,285 Seroquel users. Check the latest studies of Seroquel.
What is Arginine?
Arginine has active ingredients of l - arginine. It is often used in erection problems. eHealthMe is studying from 2,612 Arginine users. Check the latest studies of Arginine.
20 people who take Seroquel and Arginine together, and have interactions are studied.

What are the common drug interactions of Seroquel and Arginine, by gender? *:
female:
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Complex regional pain syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet))
- Initial insomnia (feeling of inadequate or poor-quality sleep)
- Weight increased
- Anaemia (lack of blood)
- Gastric ulcer haemorrhage (bleeding ulcer of stomach)
- Restless legs syndrome (a powerful urge to move your legs)
- Death
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
- Hepatic failure (liver failure)
male:
- Anxiety
- Paradoxical drug reaction
- Lyme disease (a bacterial infection that is spread to humans by infected ticks)
- Poisoning
- Sopor (sleep)
- Surgery
- Testicular failure (testicles cannot produce sperm or male hormones)
- Thyroid disorder (thyroid diseases)
- Tibia fracture (fracture of lower leg bone)
- Viral infection
What are the common drug interactions of Seroquel and Arginine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Anxiety
- Paradoxical drug reaction
- Aggression
- Increased appetite
- Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
- Tibia fracture (fracture of lower leg bone)
- Vitamin b12 decreased
20-29:
n/a
30-39:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
40-49:
- Death
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
- Hepatic failure (liver failure)
- Type 2 diabetes mellitus
50-59:
- Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
- Chronic fatigue syndrome (disorder that causes extreme fatigue)
- Drug abuse
- Fibromyalgia (a long-term condition which causes pain all over the body)
- Infection
- Lyme disease (a bacterial infection that is spread to humans by infected ticks)
- Poisoning
- Sopor (sleep)
- Testicular failure (testicles cannot produce sperm or male hormones)
- Thyroid disorder (thyroid diseases)
60+:
- Abnormal loss of weight
- Arrhythmia (irregular heartbeat)
- Muscle tightness
- Oral pain
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Sinus bradycardia (an unusually slow heartbeat due to heart disease)
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Tooth injury
- Asthenia (weakness)
- Blood pressure increased
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 40.00%
- Fibromyalgia (a long-term condition which causes pain all over the body): 5 people, 25.00%
- Cardiac Disorder: 4 people, 20.00%
- Stress And Anxiety: 4 people, 20.00%
- Insulin Resistance: 3 people, 15.00%
- High Density Lipoprotein Decreased: 3 people, 15.00%
- High Blood Cholesterol: 3 people, 15.00%
- Bone Disorder: 3 people, 15.00%
- Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 3 people, 15.00%
- Depression: 2 people, 10.00%
* Approximation only. Some reports may have incomplete information.
Do you take Seroquel and Arginine?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Seroquel and Arginine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Seroquel:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Arginine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Seroquel and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Arginine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Mati?, K., & Pele?, A. M. , "Drug-induced toxic hepatitis associated with the combination of quetiapine and fluphenazine: A case report", The European Journal of Psychiatry, 2018 Jan .
- Shah Z, Londhe V, "Influence of various media on the dissolution profiles of immediate-release quetiapine tablets in India", Dissolution Technologies, 2016 Feb .
- Mati?, K., & Pele?, A. M. , "Drug-induced toxic hepatitis associated with the combination of quetiapine and fluphenazine: A case report", The European Journal of Psychiatry, 2018 Jan .
- Shah Z, Londhe V, "Influence of various media on the dissolution profiles of immediate-release quetiapine tablets in India", Dissolution Technologies, 2016 Feb .
How the study uses the data?
The study uses data from the FDA. It is based on quetiapine fumarate and l - arginine (the active ingredients of Seroquel and Arginine, respectively), and Seroquel and Arginine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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