Seroquel and Brilinta drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Seroquel (quetiapine fumarate) and Brilinta (ticagrelor). Common drug interactions include suicide attempt among females and dyspnoea among males.
The phase IV clinical study analyzes what interactions people have when they take Seroquel and Brilinta. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.
What is Seroquel?
Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 120,285 Seroquel users. Check the latest studies of Seroquel.
What is Brilinta?
Brilinta has active ingredients of ticagrelor. It is often used in stent. eHealthMe is studying from 22,469 Brilinta users. Check the latest studies of Brilinta.
49 people who take Seroquel and Brilinta together, and have interactions are studied.

What are the common drug interactions of Seroquel and Brilinta, by gender? *:
female:
- Suicide attempt
- Vasodilatation (widening of blood vessels resulting from relaxation of smooth muscle cells within the vessel walls)
- Ageusia (loss of taste functions of the tongue)
- Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
- Chronic kidney disease
- Dyskinesia (abnormality or impairment of voluntary movement)
- Fear of disease
- Gastric hypomotility (less movement of stomach)
- Middle ear effusion (fluid in middle ear)
- Nasopharyngitis (inflammation of the nasopharynx)
male:
- Dyspnoea (difficult or laboured respiration)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Aneurysm (enlargement of an artery caused by a weakening of the artery wall)
- Chronic kidney disease
- Feeling drunk
- Haematemesis (vomiting of blood)
- Haematuria (presence of blood in urine)
- Hallucination (an experience involving the perception of something not present)
- Nasopharyngitis (inflammation of the nasopharynx)
- Platelet count decreased
What are the common drug interactions of Seroquel and Brilinta, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Cardiac disorder
- Dyspnoea (difficult or laboured respiration)
- Malaise (a feeling of general discomfort or uneasiness)
- Abdominal pain
- Anxiety
- Cholecystitis chronic (long lasting infection of gallbladder)
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Emotional distress
- General physical health deterioration (weak health status)
- Injury
30-39:
- Diarrhoea
- Urticaria (rash of round, red welts on the skin that itch intensely)
- Pancreatitis (inflammation of pancreas)
- Abdominal pain upper
- Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
- Drug hypersensitivity
- Headache (pain in head)
- Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone)
40-49:
- Hallucination, auditory (perceiving sounds without auditory stimulus)
- Hallucination, visual (seeing things that aren't there)
- Headache (pain in head)
- Injury
- Malaise (a feeling of general discomfort or uneasiness)
- Memory impairment
- Pain in extremity
- Panic attack
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Tachyphrenia (abnormally rapid mental activity)
50-59:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Foot fracture
- Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Blood cholesterol increased
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Cough
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Dizziness
60+:
- Anxiety
- Contusion (a type of hematoma of tissue in which capillaries)
- Fall
- Lower limb fracture
- Muscle twitching
- Oral pain
- Panic attack
- Pneumonia
- Tongue biting
- Viral infection
What are the existing conditions these people have? *
- High Blood Cholesterol: 14 people, 28.57%
- Depression: 12 people, 24.49%
- Stress And Anxiety: 9 people, 18.37%
- High Blood Pressure: 8 people, 16.33%
- Heart Attack: 8 people, 16.33%
- Diabetes: 8 people, 16.33%
- Blood Pressure Abnormal: 7 people, 14.29%
- Sleep Disorder: 7 people, 14.29%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 14.29%
- Pain: 6 people, 12.24%
* Approximation only. Some reports may have incomplete information.
Do you take Seroquel and Brilinta?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Seroquel and Brilinta:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Seroquel:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Brilinta:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Seroquel and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Brilinta and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Mati?, K., & Pele?, A. M. , "Drug-induced toxic hepatitis associated with the combination of quetiapine and fluphenazine: A case report", The European Journal of Psychiatry, 2018 Jan .
- Shah Z, Londhe V, "Influence of various media on the dissolution profiles of immediate-release quetiapine tablets in India", Dissolution Technologies, 2016 Feb .
- Mati?, K., & Pele?, A. M. , "Drug-induced toxic hepatitis associated with the combination of quetiapine and fluphenazine: A case report", The European Journal of Psychiatry, 2018 Jan .
- Shah Z, Londhe V, "Influence of various media on the dissolution profiles of immediate-release quetiapine tablets in India", Dissolution Technologies, 2016 Feb .
How the study uses the data?
The study uses data from the FDA. It is based on quetiapine fumarate and ticagrelor (the active ingredients of Seroquel and Brilinta, respectively), and Seroquel and Brilinta (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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