Seroquel and Embeda drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Seroquel (quetiapine fumarate) and Embeda (morphine sulfate; naltrexone hydrochloride). Common drug interactions include fall among females and faecal incontinence among males.
The phase IV clinical study analyzes what interactions people have when they take Seroquel and Embeda. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.
What is Seroquel?
Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 120,285 Seroquel users. Check the latest studies of Seroquel.
What is Embeda?
Embeda has active ingredients of morphine sulfate; naltrexone hydrochloride. eHealthMe is studying from 1,407 Embeda users. Check the latest studies of Embeda.
33 people who take Seroquel and Embeda together, and have interactions are studied.

What are the common drug interactions of Seroquel and Embeda, by gender? *:
female:
- Fall
- Alopecia (absence of hair from areas of the body)
- Bladder pain
- Blood urine present
- Constipation
- Decreased appetite
- Dizziness
- Fatigue (feeling of tiredness)
- Kidney infection
- Memory impairment
male:
- Faecal incontinence (a lack of control over passing stool)
- Hallucination, auditory (perceiving sounds without auditory stimulus)
- Renal failure (kidney dysfunction)
- Headache (pain in head)
- Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
- Adverse drug reaction
- Completed suicide (act of taking one's own life)
- Osteopenia (a condition where bone mineral density is lower than normal)
- Migraine (headache)
- Agitation (state of anxiety or nervous excitement)
What are the common drug interactions of Seroquel and Embeda, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Adverse drug reaction
- Completed suicide (act of taking one's own life)
30-39:
- Fall
- Alopecia (absence of hair from areas of the body)
- Bladder pain
- Blood urine present
- Constipation
- Decreased appetite
- Dizziness
- Fatigue (feeling of tiredness)
- Kidney infection
- Memory impairment
40-49:
- Headache (pain in head)
- Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
- Drug effect decreased
- Pneumonia
50-59:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Death
- Bone density decreased
- Emotional distress
- Multiple fractures
- Pain
- Renal failure (kidney dysfunction)
- Osteopenia (a condition where bone mineral density is lower than normal)
- Colitis (inflammation of colon)
60+:
n/a
What are the existing conditions these people have? *
- Depression: 11 people, 33.33%
- Pain: 7 people, 21.21%
- Cushing's Syndrome (obesity, a rounded face, increased fat): 7 people, 21.21%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 18.18%
- Back Pain: 6 people, 18.18%
- Binge Eating (pattern of disordered eating which consists of episodes of uncontrollable eating): 6 people, 18.18%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 18.18%
- High Blood Cholesterol: 4 people, 12.12%
- Stress And Anxiety: 4 people, 12.12%
- High Blood Pressure: 4 people, 12.12%
* Approximation only. Some reports may have incomplete information.
Do you take Seroquel and Embeda?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Seroquel and Embeda:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Seroquel:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Embeda:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Seroquel and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Embeda and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Mati?, K., & Pele?, A. M. , "Drug-induced toxic hepatitis associated with the combination of quetiapine and fluphenazine: A case report", The European Journal of Psychiatry, 2018 Jan .
- Shah Z, Londhe V, "Influence of various media on the dissolution profiles of immediate-release quetiapine tablets in India", Dissolution Technologies, 2016 Feb .
- Mati?, K., & Pele?, A. M. , "Drug-induced toxic hepatitis associated with the combination of quetiapine and fluphenazine: A case report", The European Journal of Psychiatry, 2018 Jan .
- Shah Z, Londhe V, "Influence of various media on the dissolution profiles of immediate-release quetiapine tablets in India", Dissolution Technologies, 2016 Feb .
How the study uses the data?
The study uses data from the FDA. It is based on quetiapine fumarate and morphine sulfate; naltrexone hydrochloride (the active ingredients of Seroquel and Embeda, respectively), and Seroquel and Embeda (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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