Seroquel and Gilotrif drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Seroquel (quetiapine fumarate) and Gilotrif (afatinib dimaleate). Common drug interactions include diarrhoea among females and malignant neoplasm progression among males.

The phase IV clinical study analyzes what interactions people have when they take Seroquel and Gilotrif. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Seroquel?

Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 120,285 Seroquel users. Check the latest studies of Seroquel.

What is Gilotrif?

Gilotrif has active ingredients of afatinib dimaleate. eHealthMe is studying from 6,055 Gilotrif users. Check the latest studies of Gilotrif.



On Jul, 10, 2026

11 people who take Seroquel and Gilotrif together, and have interactions are studied.

Seroquel and Gilotrif drug interactions.

What are the common drug interactions of Seroquel and Gilotrif, by gender? *:

female:

  1. Diarrhoea
  2. Decreased appetite
  3. Pneumonia
  4. Pleural effusion (water on the lungs)
  5. Rash
  6. Weight decreased
  7. Acne (skin problems that cause pimples)
  8. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  9. Central nervous system haemorrhage (bleeding in brain and surrounding)
  10. Fall

male:

  1. Malignant neoplasm progression (cancer tumour came back)
  2. Colitis (inflammation of colon)
  3. Pneumonia
  4. Discomfort
  5. Fatigue (feeling of tiredness)
  6. Nausea (feeling of having an urge to vomit)
  7. Nervous system disorder (a general class of medical conditions affecting the nervous system)
  8. Pain
  9. Sleep disorder
  10. Vomiting

What are the common drug interactions of Seroquel and Gilotrif, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Colitis (inflammation of colon)
  2. Malignant neoplasm progression (cancer tumour came back)
  3. Pneumonia
  4. Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
  5. Lactic acidosis (low ph in body tissues)

60+:

  1. Diarrhoea
  2. Decreased appetite
  3. Nausea (feeling of having an urge to vomit)
  4. Oesophagitis (inflammation of oesophagus)
  5. Pleural effusion (water on the lungs)
  6. Rash
  7. Vision blurred
  8. Weight decreased
  9. Asthenia (weakness)
  10. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)

What are the existing conditions these people have? *

  1. Lung Cancer - Non-Small Cell (lung cancer): 11 people, 100.00%
  2. Dyspnea (difficult or laboured breathing): 2 people, 18.18%
  3. Depressed Mood: 2 people, 18.18%
  4. Metastases To Central Nervous System (cancer spreads to central nervous system): 2 people, 18.18%
  5. Cough: 2 people, 18.18%
  6. Depression: 2 people, 18.18%
  7. Cancer Pain: 1 person, 9.09%
  8. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 9.09%
  9. Congestive Cardiomyopathy (weakening of heart muscle): 1 person, 9.09%
  10. Dementia (madness): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Seroquel and Gilotrif?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Seroquel and Gilotrif:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Seroquel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Gilotrif:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Seroquel and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Gilotrif and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on quetiapine fumarate and afatinib dimaleate (the active ingredients of Seroquel and Gilotrif, respectively), and Seroquel and Gilotrif (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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