Seroquel and Nucala drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Seroquel (quetiapine fumarate) and Nucala (mepolizumab). Common drug interactions include gastrooesophageal reflux disease among females and blood bilirubin increased among males.

The phase IV clinical study analyzes what interactions people have when they take Seroquel and Nucala. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Seroquel?

Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 120,285 Seroquel users. Check the latest studies of Seroquel.

What is Nucala?

Nucala has active ingredients of mepolizumab. eHealthMe is studying from 26,883 Nucala users. Check the latest studies of Nucala.

On Jul, 06, 2026

26 people who take Seroquel and Nucala together, and have interactions are studied.

What are the common drug interactions of Seroquel and Nucala, by gender? *:

female:

Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Wheezing (a high-pitched whistling sound made while you breath)
Blood bilirubin increased
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
Cardiac murmur (an heart sound in valve abnormality)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Hepatic enzyme increased
Hepatotoxicity (chemical-driven liver damage)
Hypomania (a mild form of mania, marked by elation and hyperactivity)

male:

Blood bilirubin increased
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
Lung neoplasm malignant (cancer tumour of lung)
Nasal polyps (masses that develop in the lining of the nose)
Nausea (feeling of having an urge to vomit)
Oedema peripheral (superficial swelling)
Pneumonia
Psychotic disorder
Rhinitis allergic (inflammation of the nasal airways due to allergy)
Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands)

What are the common drug interactions of Seroquel and Nucala, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Ankle fracture
Arthralgia (joint pain)
Fall
Joint dislocation (a joint position is changed from normal position)

40-49:

n/a

50-59:

Hepatotoxicity (chemical-driven liver damage)
Hypomania (a mild form of mania, marked by elation and hyperactivity)
Jaundice cholestatic
Lung neoplasm malignant (cancer tumour of lung)
Nasal polyps (masses that develop in the lining of the nose)
Nausea (feeling of having an urge to vomit)
Oedema peripheral (superficial swelling)
Pneumonia
Psychotic disorder
Rhinitis allergic (inflammation of the nasal airways due to allergy)

60+:

Death
Tooth erosion (dissolving teeth)

What are the existing conditions these people have? *

Psychotic Disorder: 17 people, 65.38%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 17 people, 65.38%
Hypomania (a mild form of mania, marked by elation and hyperactivity): 17 people, 65.38%
Depression: 17 people, 65.38%
Hiv Infection: 15 people, 57.69%
Pain In Extremity: 6 people, 23.08%
Asthma: 6 people, 23.08%
Seasonal Allergy (allergic condition due to certain season): 3 people, 11.54%
Rhinitis Perennial (an inflammatory condition of the nose characterized by nasal obstruction, sneezing, itching): 3 people, 11.54%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 11.54%

* Approximation only. Some reports may have incomplete information.

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