Sertraline and Constulose drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Sertraline (sertraline hydrochloride) and Constulose (lactulose). Common drug interactions include rash among females and abdominal discomfort among males.
The phase IV clinical study analyzes what interactions people have when they take Sertraline and Constulose. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.
What is Sertraline?
Sertraline has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 153,305 Sertraline users. Check the latest studies of Sertraline.
What is Constulose?
Constulose has active ingredients of lactulose. eHealthMe is studying from 364 Constulose users. Check the latest studies of Constulose.
17 people who take Sertraline and Constulose together, and have interactions are studied.

What are the common drug interactions of Sertraline and Constulose, by gender? *:
female:
- Rash
- Abdominal discomfort
- Candidiasis (candidiasis or thrush is a fungal infection)
- Chronic kidney disease
- Death
- Hospitalisation
- Hot flush (sudden feelings of heat)
- Infection
- Night sweats (sweating in night)
- Non-cardiac chest pain
male:
- Abdominal discomfort
- Contusion (a type of hematoma of tissue in which capillaries)
- Learning disability (difficulty in learning)
- Libido disorder (a sexual dysfunction relating to loss of sexual desire)
- Malaise (a feeling of general discomfort or uneasiness)
- Mass
- Memory impairment
- Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
- Neuropathy peripheral (surface nerve damage)
- Overdose
What are the common drug interactions of Sertraline and Constulose, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Contusion (a type of hematoma of tissue in which capillaries)
- Foot fracture
- Haemorrhage (bleeding)
- Joint injury
- Mass
- Pain in extremity
40-49:
- Infection
50-59:
- Chronic kidney disease
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
60+:
- Candidiasis (candidiasis or thrush is a fungal infection)
- Death
- Hot flush (sudden feelings of heat)
- Night sweats (sweating in night)
- Pyrexia (fever)
- Rash
- Tooth infection
- Tremor (trembling or shaking movements in one or more parts of your body)
What are the existing conditions these people have? *
- Multiple Myeloma (cancer of the plasma cells): 4 people, 23.53%
- Pain: 3 people, 17.65%
- Indigestion: 2 people, 11.76%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 11.76%
- Itching: 2 people, 11.76%
- Insomnia (sleeplessness): 2 people, 11.76%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 11.76%
- High Blood Pressure: 1 person, 5.88%
- Cystic Fibrosis (disease of the secretary glands): 1 person, 5.88%
- Diabetes: 1 person, 5.88%
* Approximation only. Some reports may have incomplete information.
Do you take Sertraline and Constulose?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Sertraline (153,305 reports)
- Constulose (364 reports)
Browse all drug interactions of Sertraline and Constulose:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Sertraline:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Constulose:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Sertraline and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Constulose and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .
- Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on sertraline hydrochloride and lactulose (the active ingredients of Sertraline and Constulose, respectively), and Sertraline and Constulose (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Amlodipine and Balance Disorder for Men aged 50-59 - now
- Could Theophyl cause Hypothyroidism? - 12 seconds ago
- Drug interactions of Locoid and Zolpidem - 14 seconds ago
- Could Ambien cause Diarrhea Haemorrhagic? - 17 seconds ago
- Perampanel and Vimpat drug interactions for men aged 60+ - 19 seconds ago
- Prostatic Disorder and Urination - Painful - 23 seconds ago
- Could Gabapentin cause Skin Discoloration? - 23 seconds ago
- Atrophy and drugs of ingredients of etanercept - 23 seconds ago
- Neupogen and Chest Pain for Women aged 20-29 - 24 seconds ago
- Neupogen and Painful Chest for Women aged 20-29 - 25 seconds ago