Serzone and Atacand drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Serzone (nefazodone hydrochloride) and Atacand (candesartan cilexetil). Common drug interactions include completed suicide among females and diabetes mellitus among males.

The phase IV clinical study analyzes what interactions people have when they take Serzone and Atacand. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Serzone?

Serzone has active ingredients of nefazodone hydrochloride. It is often used in depression. eHealthMe is studying from 7,695 Serzone users. Check the latest studies of Serzone.

What is Atacand?

Atacand has active ingredients of candesartan cilexetil. It is often used in high blood pressure. eHealthMe is studying from 22,473 Atacand users. Check the latest studies of Atacand.



On Jul, 11, 2026

11 people who take Serzone and Atacand together, and have interactions are studied.

Serzone and Atacand drug interactions.

What are the common drug interactions of Serzone and Atacand, by gender? *:

female:

  1. Completed suicide (act of taking one's own life)
  2. Drug ineffective
  3. Drug toxicity
  4. Hepatic congestion (liver congestion)
  5. Pancreatic disorder
  6. Pulmonary congestion (congestion in the lungs)
  7. Renal disorder (kidney disease)
  8. Bacterial infection
  9. Cardiac disorder
  10. Cell death

male:

  1. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  2. Diabetic complication
  3. Bipolar disorder (mood disorder)
  4. Chronic kidney disease
  5. Dizziness
  6. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  7. Injury
  8. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  9. Pain
  10. Renal failure (kidney dysfunction)

What are the common drug interactions of Serzone and Atacand, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Alanine aminotransferase increased
  2. Dizziness

40-49:

  1. Type 2 diabetes mellitus
  2. Diabetic complication
  3. Hyperglycaemia (high blood sugar)
  4. Pain
  5. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  6. Bacterial infection
  7. Bipolar disorder (mood disorder)
  8. Cardiac disorder
  9. Cell death
  10. Completed suicide (act of taking one's own life)

50-59:

  1. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  2. Coronary artery bypass
  3. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  4. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

60+:

  1. Chronic kidney disease
  2. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  3. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  4. Oedema (fluid collection in tissue)
  5. Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

  1. Sleep Disorder: 4 people, 36.36%
  2. Stress And Anxiety: 3 people, 27.27%
  3. Insomnia (sleeplessness): 3 people, 27.27%
  4. Bipolar Disorder (mood disorder): 3 people, 27.27%
  5. Restless Leg Syndrome (a powerful urge to move your legs): 2 people, 18.18%
  6. Diabetes: 2 people, 18.18%
  7. Pain: 1 person, 9.09%
  8. Neuropathy Peripheral (surface nerve damage): 1 person, 9.09%
  9. Neuralgia (pain in one or more nerves): 1 person, 9.09%
  10. Hyperuricaemia (level of uric acid in the blood that is abnormally high): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Serzone and Atacand?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Serzone and Atacand:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Serzone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Atacand:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Serzone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Atacand and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on nefazodone hydrochloride and candesartan cilexetil (the active ingredients of Serzone and Atacand, respectively), and Serzone and Atacand (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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