Serzone and Clozapine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Serzone (nefazodone hydrochloride) and Clozapine (clozapine). Common drug interactions include blood cholesterol increased among females and completed suicide among males.

The phase IV clinical study analyzes what interactions people have when they take Serzone and Clozapine. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Serzone?

Serzone has active ingredients of nefazodone hydrochloride. It is often used in depression. eHealthMe is studying from 7,695 Serzone users. Check the latest studies of Serzone.

What is Clozapine?

Clozapine has active ingredients of clozapine. It is often used in schizophrenia. eHealthMe is studying from 83,728 Clozapine users. Check the latest studies of Clozapine.

On Jul, 10, 2026

17 people who take Serzone and Clozapine together, and have interactions are studied.

Serzone and Clozapine drug interactions.

What are the common drug interactions of Serzone and Clozapine, by gender? *:

female:

Blood cholesterol increased
Obesity (having too much body fat)
Renal failure (kidney dysfunction)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Type 2 diabetes mellitus
Diabetes mellitus inadequate control
Diabetes mellitus insulin-dependent
Fall
Foot fracture
Hyperglycaemia (high blood sugar)

male:

Completed suicide (act of taking one's own life)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Gingival hyperplasia (overgrowth of gums)
Ileus (a painful obstruction of the ileum or other part of the intestine)
Intestinal obstruction
Loss of consciousness
Oesophagitis (inflammation of oesophagus)
Overdose
Suicide attempt
Throat tightness

What are the common drug interactions of Serzone and Clozapine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Overdose
Suicide attempt

30-39:

Completed suicide (act of taking one's own life)
Diabetes mellitus inadequate control
Diabetes mellitus insulin-dependent
Hyperglycaemia (high blood sugar)

40-49:

Type 2 diabetes mellitus
Cardiac disorder
Drooling (drop saliva uncontrollably from the mouth)
Dysphagia (a condition in which swallowing is difficult or painful)
Gingival hyperplasia (overgrowth of gums)
Ileus (a painful obstruction of the ileum or other part of the intestine)
Intestinal obstruction
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Throat tightness
Blood cholesterol increased

50-59:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Loss of consciousness
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

60+:

Fall
Foot fracture
Neutropenia (an abnormally low number of neutrophils)

What are the existing conditions these people have? *

Post-Traumatic Stress Disorder: 2 people, 11.76%
Insomnia (sleeplessness): 2 people, 11.76%
Bipolar Disorder (mood disorder): 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

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