Serzone and Glyburide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Serzone (nefazodone hydrochloride) and Glyburide (glyburide). Common drug interactions include irritable bowel syndrome among females and back pain among males.

The phase IV clinical study analyzes what interactions people have when they take Serzone and Glyburide. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Serzone?

Serzone has active ingredients of nefazodone hydrochloride. It is often used in depression. eHealthMe is studying from 7,695 Serzone users. Check the latest studies of Serzone.

What is Glyburide?

Glyburide has active ingredients of glyburide. It is often used in diabetes. eHealthMe is studying from 38,448 Glyburide users. Check the latest studies of Glyburide.

On Jul, 13, 2026

45 people who take Serzone and Glyburide together, and have interactions are studied.

Serzone and Glyburide drug interactions.

What are the common drug interactions of Serzone and Glyburide, by gender? *:

female:

Irritable bowel syndrome
Pain in extremity
Upper respiratory tract infection
Acromegaly (body produces too much growth hormone, leading to excess growth of body tissues)
Acute sinusitis
Blood cholesterol increased
Constipation
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Gigantism (excessive growth and height)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)

male:

Back pain
Cardiac failure congestive
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Diabetes mellitus inadequate control
Duodenitis (inflammation of the duodenum)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Gallop rhythm present (extra heart beat sound present)
Haematocrit decreased
Haemoglobin decreased

What are the common drug interactions of Serzone and Glyburide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Gastroenteritis (inflammation of stomach and intestine)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hepatic steatosis (fatty liver disease)
Tinea infection (fungal skin infection)
Vision blurred

10-19:

n/a

20-29:

Blood pressure decreased
Cardiac disorder
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Suicide attempt

30-39:

Back pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Overdose
Pleurisy (inflammation of the pleurae, which causes pain when breathing)
Suicidal ideation
Back injury
Chest pain
Contusion (a type of hematoma of tissue in which capillaries)
Diabetes mellitus inadequate control

40-49:

Diabetic complication
Hyperglycaemia (high blood sugar)
Bipolar disorder (mood disorder)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Alanine aminotransferase increased
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Aspartate aminotransferase increased
Astigmatism (refractive error of the eye in which parallel rays of light from an external source do not converge on a single focal point on the retina)
Back pain
Blood glucose increased

50-59:

Oedema peripheral (superficial swelling)
Pancreatic mass
Pancreatitis (inflammation of pancreas)
Simple partial seizures (seizures which affect only a small region of the brain)
Vomiting
Weight increased
Wound infection
Dysphagia (a condition in which swallowing is difficult or painful)
Hyperlipidaemia (presence of excess lipids in the blood)
Nausea (feeling of having an urge to vomit)

60+:

Renal failure acute (rapid kidney dysfunction)
Sedation
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Rales (an abnormal respiratory sound characterized by fine crackles)
Social avoidant behaviour (avoiding social connection a personality disorder)
Acidosis (build-up of carbon dioxide in the blood)
Acute myocardial infarction (acute heart attack)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Blood creatinine increased
Blood glucose decreased

What are the existing conditions these people have? *

Stress And Anxiety: 8 people, 17.78%
Sleep Disorder: 6 people, 13.33%
Insomnia (sleeplessness): 5 people, 11.11%
Bipolar Disorder (mood disorder): 5 people, 11.11%
Tremor (trembling or shaking movements in one or more parts of your body): 3 people, 6.67%
Hypoglycemia (low blood sugar): 3 people, 6.67%
Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 3 people, 6.67%
Agitation (state of anxiety or nervous excitement): 3 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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