Serzone and Nitrostat drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Serzone (nefazodone hydrochloride) and Nitrostat (nitroglycerin). Common drug interactions include arthritis among females and back pain among males.
The phase IV clinical study analyzes what interactions people have when they take Serzone and Nitrostat. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.
What is Serzone?
Serzone has active ingredients of nefazodone hydrochloride. It is often used in depression. eHealthMe is studying from 7,695 Serzone users. Check the latest studies of Serzone.
What is Nitrostat?
Nitrostat has active ingredients of nitroglycerin. It is often used in chest pain. eHealthMe is studying from 14,082 Nitrostat users. Check the latest studies of Nitrostat.
22 people who take Serzone and Nitrostat together, and have interactions are studied.

What are the common drug interactions of Serzone and Nitrostat, by gender? *:
female:
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Blood creatine phosphokinase increased
- Cardiac murmur (an heart sound in valve abnormality)
- Chronic kidney disease
- Diarrhoea
- Dysphagia (a condition in which swallowing is difficult or painful)
- Dyspnoea exertional (breathlessness or shortness of breath)
- Emotional disorder
- Excessive eye blinking (excessive blinking is dry eyes)
male:
- Back pain
- Dizziness
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Blood creatinine increased
- Blood immunoglobulin g increased
- Bone disorder
- Cardiac arrest
- Cardiac asthma (wheezing, coughing or shortness of breath due to congestive heart failure)
- Cardiac failure congestive
- Cardiomegaly (increased size of heart than normal)
What are the common drug interactions of Serzone and Nitrostat, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Diabetes mellitus inadequate control
- Hyperglycaemia (high blood sugar)
- Back pain
- Chronic kidney disease
- Gait disturbance
- Nephrogenic anaemia (anaemia due to kidney disease)
- Pain in extremity
- Renal failure (kidney dysfunction)
- Nephropathy (damage to or disease of a kidney)
50-59:
- Hepatic steatosis (fatty liver disease)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Obstructive airways disorder (a progressive disease that makes it hard to breathe)
- Renal failure (kidney dysfunction)
- Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
- Abdominal pain
- Alanine aminotransferase increased
- Blood creatine phosphokinase increased
- Chronic kidney disease
- Diarrhoea
60+:
- Arthralgia (joint pain)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
- Arthropathy
- Blood creatinine increased
- Blood immunoglobulin g increased
- Bone disorder
- Bone pain
- Cardiac arrest
- Cardiac asthma (wheezing, coughing or shortness of breath due to congestive heart failure)
What are the existing conditions these people have? *
- Arrhythmias (irregular heartbeat): 6 people, 27.27%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 6 people, 27.27%
- Multiple Myeloma (cancer of the plasma cells): 6 people, 27.27%
- Stable Angina (a constant chest pain): 6 people, 27.27%
- High Blood Pressure: 4 people, 18.18%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 18.18%
- Pain: 3 people, 13.64%
- Asthma: 2 people, 9.09%
- Diabetes: 2 people, 9.09%
- Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Serzone and Nitrostat?
- Personalize this study to your gender, age, symptoms and drugs
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Serzone and Nitrostat:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Serzone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Nitrostat:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Serzone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Nitrostat and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on nefazodone hydrochloride and nitroglycerin (the active ingredients of Serzone and Nitrostat, respectively), and Serzone and Nitrostat (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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