Serzone and Temaz drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Serzone (nefazodone hydrochloride) and Temaz (temazepam). Common drug interactions include tardive dyskinesia among females and oedema peripheral among males.

The phase IV clinical study analyzes what interactions people have when they take Serzone and Temaz. It is created by eHealthMe based on reports of 77 people who take the same drugs from the FDA, and is updated regularly.

What is Serzone?

Serzone has active ingredients of nefazodone hydrochloride. It is often used in depression. eHealthMe is studying from 7,695 Serzone users. Check the latest studies of Serzone.

What is Temaz?

Temaz has active ingredients of temazepam. It is often used in insomnia. eHealthMe is studying from 42,293 Temaz users. Check the latest studies of Temaz.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 21, 2026

77 people who take Serzone and Temaz together, and have interactions are studied.

What are the common drug interactions of Serzone and Temaz, by gender? *:

female:

Tardive dyskinesia (a disorder that involves involuntary movements)
Breast pain
Breast tenderness
Chronic kidney disease
Fear
Increased appetite
Leukopenia (less number of white blood cells in blood)
Libido decreased (loss of interest in sex)
Memory impairment
Tremor (trembling or shaking movements in one or more parts of your body)

male:

Oedema peripheral (superficial swelling)
Arthralgia (joint pain)
Erectile dysfunction
Hypoaesthesia (reduced sense of touch or sensation)
Spinal osteoarthritis (joint cartilage loss in spine)
Anaemia (lack of blood)
Blood cholesterol increased
Diarrhoea
General physical health deterioration (weak health status)
Hyperlipidaemia (presence of excess lipids in the blood)

What are the common drug interactions of Serzone and Temaz, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Diabetic eye disease
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Ketoacidosis (high concentrations of ketone bodies in blood)

40-49:

Diabetic coma
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetes mellitus non-insulin-dependent
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hypertension (high blood pressure)
Nephrolithiasis (calculi in the kidneys)
Rectal haemorrhage (bleeding from anus)
Diabetes mellitus inadequate control
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Hyperglycaemia (high blood sugar)

50-59:

Constipation
Hypoaesthesia (reduced sense of touch or sensation)
Pain in extremity
Spinal osteoarthritis (joint cartilage loss in spine)
Syncope (loss of consciousness with an inability to maintain postural tone)
Arthralgia (joint pain)
Asthenia (weakness)
Deformity (disfigurement)
Injury
Osteoarthritis (a joint disease caused by cartilage loss in a joint)

60+:

Oedema peripheral (superficial swelling)
Fatigue (feeling of tiredness)
Atelectasis (partial or complete collapse of the lung)
Osteonecrosis of jaw (death of bone of jaw)
Chest pain
Vitreous floaters (spots before the eyes)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Confusional state
Diarrhoea
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 21 people, 27.27%
Pain: 16 people, 20.78%
Prostate Cancer: 9 people, 11.69%
Bone Density Abnormal: 9 people, 11.69%
Stress And Anxiety: 7 people, 9.09%
Stable Angina (a constant chest pain): 6 people, 7.79%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 7.79%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 6 people, 7.79%
Arrhythmias (irregular heartbeat): 6 people, 7.79%
Sleep Disorder: 5 people, 6.49%

* Approximation only. Some reports may have incomplete information.

Do you take Serzone and Temaz?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously