Serzone and Ziagen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Serzone (nefazodone hydrochloride) and Ziagen (abacavir sulfate). Common drug interactions include pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Serzone and Ziagen. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Serzone?

Serzone has active ingredients of nefazodone hydrochloride. It is often used in depression. eHealthMe is studying from 7,695 Serzone users. Check the latest studies of Serzone.

What is Ziagen?

Ziagen has active ingredients of abacavir sulfate. It is often used in hiv infection. eHealthMe is studying from 7,626 Ziagen users. Check the latest studies of Ziagen.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

12 people who take Serzone and Ziagen together, and have interactions are studied.

What are the common drug interactions of Serzone and Ziagen, by gender? *:

female:

n/a

male:

Pyrexia (fever)
Malaise (a feeling of general discomfort or uneasiness)
Bradycardia (abnormally slow heart action)
Drug eruption (adverse drug reaction of the skin)
Headache (pain in head)
Hypersensitivity
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Incoherent (talking in a confused and unclear way)
Miosis (constriction of the pupil of the eye, resulting from a normal response to an increase in light)
Myalgia (muscle pain)

What are the common drug interactions of Serzone and Ziagen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Difficulty in walking
Hypoaesthesia (reduced sense of touch or sensation)
Paralysis

30-39:

Blood testosterone decreased
Diarrhoea
Dizziness (excl vertigo)
Dysstasia (difficulty in standing)
Fall
Haemoglobin decreased
Headache (pain in head)
Hiv wasting syndrome (aids wasting syndrome occurs when you have aids and lose at least 10% of your body weight -- especially muscle)
Infection
Malaise (a feeling of general discomfort or uneasiness)

40-49:

Back pain
Chronic kidney disease
Gait disturbance
Malaise (a feeling of general discomfort or uneasiness)
Nephrogenic anaemia (anaemia due to kidney disease)
Pain in extremity
Pyrexia (fever)
Renal failure (kidney dysfunction)
Anaemia (lack of blood)
Arthralgia (joint pain)

50-59:

Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Blood alkaline phosphatase nos increased
Myalgia (muscle pain)
Pyrexia (fever)
White blood cell count increased
Abdominal tenderness
Confusion
Headache (pain in head)
Hypersensitivity
Nausea (feeling of having an urge to vomit)

60+:

n/a

What are the existing conditions these people have? *

High Blood Pressure: 2 people, 16.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 16.67%
Abdominal Discomfort: 2 people, 16.67%
Pain: 2 people, 16.67%
Nausea (feeling of having an urge to vomit): 1 person, 8.33%
Nasopharyngitis (inflammation of the nasopharynx): 1 person, 8.33%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 1 person, 8.33%
Cardiac Disorder: 1 person, 8.33%
Cough: 1 person, 8.33%
Eye Disorder: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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