Silvadene and Norco drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Silvadene (silver sulfadiazine) and Norco (acetaminophen; hydrocodone bitartrate). Common drug interactions include acute respiratory failure among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Silvadene and Norco. It is created by eHealthMe based on reports of 84 people who take the same drugs from the FDA, and is updated regularly.

What is Silvadene?

Silvadene has active ingredients of silver sulfadiazine. eHealthMe is studying from 1,161 Silvadene users. Check the latest studies of Silvadene.

What is Norco?

Norco has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 74,063 Norco users. Check the latest studies of Norco.

On Jul, 14, 2026

84 people who take Silvadene and Norco together, and have interactions are studied.

What are the common drug interactions of Silvadene and Norco, by gender? *:

female:

Acute respiratory failure
Anaemia (lack of blood)
Anal cancer
Anorectal disorder
Anxiety
Arthropathy
Asthenia (weakness)
B-lymphocyte abnormalities (abnormal population of b lymphocytes in the blood, bone marrow, or tissues)
Balance disorder
Blood phosphorus decreased

male:

Dyspnoea (difficult or laboured respiration)
Fall
Depression
Drug ineffective
Feeling hot
Head injury
Hip fracture
Lacrimation increased
Nephrolithiasis (calculi in the kidneys)
Peripheral coldness

What are the common drug interactions of Silvadene and Norco, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Death

30-39:

Cytomegalovirus gastritis (virus infection of stomach)

40-49:

Depression
Drug ineffective
Affective disorder (mental disorder)
Emotional disorder
Feeling hot
Head injury
Intestinal obstruction
Lacrimation increased
Peripheral coldness
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

50-59:

Nausea (feeling of having an urge to vomit)
Neoplasm progression (growth of tumour)
Nephrogenic anaemia (anaemia due to kidney disease)
Neuroma (tumour of nerve tissue)
Pleural effusion (water on the lungs)
Pneumonia
Pruritus (severe itching of the skin)
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)
Secondary hyperthyroidism

60+:

Chronic kidney disease
Fatigue (feeling of tiredness)
Pneumonia
Renal failure (kidney dysfunction)
Abdominal pain
Abdominal pain upper
Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue)
Anaemia (lack of blood)
Anal cancer
Anorectal disorder

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 18 people, 21.43%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 9.52%
High Blood Pressure: 6 people, 7.14%
Hypersensitivity: 5 people, 5.95%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 5.95%
Depression: 5 people, 5.95%
Constipation: 5 people, 5.95%

* Approximation only. Some reports may have incomplete information.

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