Simcor and Magnesium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Simcor (niacin; simvastatin) and Magnesium (magnesium). Common drug interactions include pruritus among females and flushing among males.

The phase IV clinical study analyzes what interactions people have when they take Simcor and Magnesium. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.

What is Simcor?

Simcor has active ingredients of niacin; simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 11,604 Simcor users. Check the latest studies of Simcor.

What is Magnesium?

Magnesium has active ingredients of magnesium. It is often used in constipation. eHealthMe is studying from 121,144 Magnesium users. Check the latest studies of Magnesium.

On Jul, 07, 2026

59 people who take Simcor and Magnesium together, and have interactions are studied.

What are the common drug interactions of Simcor and Magnesium, by gender? *:

female:

Pruritus (severe itching of the skin)
Abdominal discomfort
Impaired healing
Injection site pain
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Abdominal distension
Dyspnoea exertional (breathlessness or shortness of breath)
Fatigue (feeling of tiredness)
Feeling hot
Urine output decreased

male:

Flushing (the warm, red condition of human skin)
Arthralgia (joint pain)
Comminuted fracture (bone has broken into several pieces)
Epistaxis (bleed from the nose)
Fall
Femur fracture
Fracture delayed union (delayed cure of broken bone)
Fracture displacement
Fracture nonunion (permanent failure of healing following a broken bone)
Gait disturbance

What are the common drug interactions of Simcor and Magnesium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Impaired healing
Joint range of motion decreased (disease of joint movement)
Limb asymmetry (consistent task discrepancy between the two lower limbs)
Muscular weakness (muscle weakness)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteopenia (a condition where bone mineral density is lower than normal)
Pain in extremity
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pathological fracture (broken bone caused by disease)
Procedural dizziness

40-49:

Flushing (the warm, red condition of human skin)
Feeling hot
General physical health deterioration (weak health status)
Intracranial tumour haemorrhage (bleeding tumour in brain)
Irritability
Paraplegia (paralysis of the legs and lower body)
Pruritus (severe itching of the skin)
Skin burning sensation

50-59:

Feeling hot
Flushing (the warm, red condition of human skin)
Abdominal discomfort
Foot fracture
Impaired healing
Injection site haemorrhage (bleeding from injection site)
Injection site pain
Seasonal allergy (allergic condition due to certain season)
Erythema (redness of the skin)
Depressed mood

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Flushing (the warm, red condition of human skin)
Muscle spasms (muscle contraction)
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
Asthenia (weakness)
Cardiomyopathy (weakening of the heart muscle)
Renal impairment (severely reduced kidney function)
Viral pericarditis (inflammation of the pericardium (the fibrous sac surrounding the heart) caused by viral infection)
Myalgia (muscle pain)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 13.56%
High Density Lipoprotein Decreased: 6 people, 10.17%
High Blood Pressure: 6 people, 10.17%
Low Density Lipoprotein Increased (cholesterol increased in blood): 5 people, 8.47%
Pain: 4 people, 6.78%
Osteoporosis (bones weak and more likely to break): 4 people, 6.78%
Migraine (headache): 4 people, 6.78%
Infection: 4 people, 6.78%
Depression: 3 people, 5.08%
Dyslipidaemia (abnormal amount of lipids): 3 people, 5.08%

* Approximation only. Some reports may have incomplete information.

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