Simethicone and Diprivan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Simethicone (simethicone) and Diprivan (propofol). Common drug interactions include dysmenorrhoea among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Simethicone and Diprivan. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Simethicone?

Simethicone has active ingredients of simethicone. It is often used in gas. eHealthMe is studying from 6,762 Simethicone users. Check the latest studies of Simethicone.

What is Diprivan?

Diprivan has active ingredients of propofol. eHealthMe is studying from 6,496 Diprivan users. Check the latest studies of Diprivan.

On Jul, 15, 2026

36 people who take Simethicone and Diprivan together, and have interactions are studied.

Simethicone and Diprivan drug interactions.

What are the common drug interactions of Simethicone and Diprivan, by gender? *:

female:

Dysmenorrhoea (painful menstruation)
Fatigue (feeling of tiredness)
Lymphocyte count decreased
Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
Migraine (headache)
Uterine haemorrhage (uterine bleeding)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Blood creatinine increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cough

male:

Pyrexia (fever)
Hypoxia (low oxygen in tissues)
Acute lymphocytic leukaemia (cancer of the white blood cells)
Agitation (state of anxiety or nervous excitement)
Ammonia increased
Anion gap increased
Apnoea (suspension of external breathing)
Ascites (accumulation of fluid in the abdominal cavity)
Atelectasis (partial or complete collapse of the lung)
Blood albumin decreased

What are the common drug interactions of Simethicone and Diprivan, by age (0-1 to 60+)? *:

0-1:

Abdominal infection
Activated partial thromboplastin time prolonged
Alanine aminotransferase increased
Ammonia decreased
Anaemia (lack of blood)
Anion gap increased
Aspartate aminotransferase increased
Blast cell count increased
Blood albumin decreased
Blood calcium decreased

2-9:

n/a

10-19:

Pericardial effusion (fluid around the heart)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Pyrexia (fever)
Respiratory disorder (respiratory disease)
Sensory disturbance (sense disturbance)
Splenomegaly (enlargement of spleen)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Tachypnoea (a condition of rapid breathing over 20 per minute)
Testicular swelling (swelling of testes)
Transaminases increased

20-29:

n/a

30-39:

n/a

40-49:

Abdominal distension
Abdominal pain
Device dislocation
Dysmenorrhoea (painful menstruation)
Fatigue (feeling of tiredness)
Lymphocyte count decreased
Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
Migraine (headache)
Uterine haemorrhage (uterine bleeding)
Haemangioma of skin (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in the skin or internal organs)

50-59:

Acute respiratory failure
Cardiac failure congestive
Chronic kidney disease
Cytomegalovirus viraemia (cytomegalo virus in blood stream)
Fluid overload (too much fluid in the blood)
Fluid retention (an abnormal accumulation of fluid in the blood)
Gastric cancer (stomach cancer)
Hypoxia (low oxygen in tissues)
Leukopenia (less number of white blood cells in blood)
Neutropenia (an abnormally low number of neutrophils)

60+:

Blood creatinine increased
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Intracranial aneurysm (bulging, weak area in the wall of a cranial artery)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Nephrogenic anaemia (anaemia due to kidney disease)
Polyuria (production of too much dilute urine)
Pyelonephritis (inflammation of kidney caused by bacteria)
Pyrexia (fever)
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)

What are the existing conditions these people have? *

High Blood Pressure: 17 people, 47.22%
Depression: 17 people, 47.22%
Cough: 16 people, 44.44%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 16 people, 44.44%
Indigestion: 15 people, 41.67%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 13 people, 36.11%
Back Pain: 12 people, 33.33%
Pain: 12 people, 33.33%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 12 people, 33.33%
Joint Pain: 12 people, 33.33%

* Approximation only. Some reports may have incomplete information.

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