Sinemet and Insulin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sinemet (carbidopa; levodopa) and Insulin (insulin pork). Common drug interactions include dyskinesia among females and nightmare among males.

The phase IV clinical study analyzes what interactions people have when they take Sinemet and Insulin. It is created by eHealthMe based on reports of 83 people who take the same drugs from the FDA, and is updated regularly.

What is Sinemet?

Sinemet has active ingredients of carbidopa; levodopa. It is often used in parkinson's disease. eHealthMe is studying from 29,601 Sinemet users. Check the latest studies of Sinemet.

What is Insulin?

Insulin has active ingredients of insulin pork. It is often used in diabetes. eHealthMe is studying from 50,203 Insulin users. Check the latest studies of Insulin.

On Jul, 11, 2026

83 people who take Sinemet and Insulin together, and have interactions are studied.

What are the common drug interactions of Sinemet and Insulin, by gender? *:

female:

Dyskinesia (abnormality or impairment of voluntary movement)
Dyspepsia (indigestion)
Fibroma (tumours that are composed of fibrous or connective tissue)
Freezing phenomenon
Hallucination, visual (seeing things that aren't there)
Inflammation
Memory impairment
Mobility decreased (ability to move is reduced)
Muscle rigidity (muscle stiffness)
Muscle spasms (muscle contraction)

male:

Nightmare (unpleasant dream)
Hallucination (an experience involving the perception of something not present)
Blood glucose decreased
Headache (pain in head)
Psychotic disorder
Aggression
Depression
Fall
Somnolence (a state of near-sleep, a strong desire for sleep)
Subdural haematoma (blood collects between the skull and the surface of the brain)

What are the common drug interactions of Sinemet and Insulin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal distension
Back pain
Dyspareunia (painful sexual intercourse)
Fatigue (feeling of tiredness)
Genital haemorrhage (bleeding from genital)
Headache (pain in head)
Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
Monoplegia (a paralysis of a single limb)
Muscle fatigue (a condition in which muscles cannot exert their normal force)
Adverse event

40-49:

Chest pain
Dizziness
Palpitations (feelings or sensations that your heart is pounding or racing)

50-59:

Chronic kidney disease
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Dysarthria (speech disorder)
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
Renal failure (kidney dysfunction)
Abnormal dreams
Blood glucose decreased
Blood glucose increased

60+:

Hallucination (an experience involving the perception of something not present)
Constipation
Abdominal pain
Hallucination, visual (seeing things that aren't there)
Headache (pain in head)
Asthenia (weakness)
Confusional state
Feeling hot
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Memory impairment

What are the existing conditions these people have? *

Hallucinations (sensations that appear real but are created by your mind): 12 people, 14.46%
Delusion (a false belief or opinion): 12 people, 14.46%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 8 people, 9.64%
High Blood Pressure: 5 people, 6.02%
Dementia (madness): 5 people, 6.02%

* Approximation only. Some reports may have incomplete information.

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