Sinemet and Rivaroxaban drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sinemet (carbidopa; levodopa) and Rivaroxaban (rivaroxaban). Common drug interactions include restlessness among females and balance disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Sinemet and Rivaroxaban. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Sinemet?

Sinemet has active ingredients of carbidopa; levodopa. It is often used in parkinson's disease. eHealthMe is studying from 29,601 Sinemet users. Check the latest studies of Sinemet.

What is Rivaroxaban?

Rivaroxaban has active ingredients of rivaroxaban. It is often used in blood clots. eHealthMe is studying from 26,544 Rivaroxaban users. Check the latest studies of Rivaroxaban.

On Aug, 11, 2026

28 people who take Sinemet and Rivaroxaban together, and have interactions are studied.

Sinemet and Rivaroxaban drug interactions.

What are the common drug interactions of Sinemet and Rivaroxaban, by gender? *:

female:

Restlessness (not able to rest)
Scar
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Stoma site reaction (reaction at abdominal opening)
Cerebral haemorrhage (bleeding within the brain)
Hemiplegia (paralysis of one side of the body)
Thalamus haemorrhage (bleeding in thalamus)
Abdominal pain
Aggression
Confusional state

male:

Balance disorder
Insomnia (sleeplessness)
Headache (pain in head)
Injury
Lethargy (tiredness)
Temperature intolerance (inability to go in temperature)
Abnormal dreams
Aggression
Anger
Angina pectoris (chest pain due to ischemia of the heart muscle)

What are the common drug interactions of Sinemet and Rivaroxaban, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Balance disorder
Insomnia (sleeplessness)
Dizziness
Headache (pain in head)
Injury
Lethargy (tiredness)
Temperature intolerance (inability to go in temperature)
Abnormal dreams
Anger
Angina pectoris (chest pain due to ischemia of the heart muscle)

What are the existing conditions these people have? *

Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 12 people, 42.86%
Arrhythmias (irregular heartbeat): 8 people, 28.57%
Stable Angina (a constant chest pain): 7 people, 25.00%
Quit Smoking: 7 people, 25.00%
Heart Attack: 7 people, 25.00%
Sleep Disorder: 5 people, 17.86%
Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 4 people, 14.29%
Hyperthyroidism (over activity of the thyroid gland): 4 people, 14.29%
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 4 people, 14.29%
Depression: 4 people, 14.29%

* Approximation only. Some reports may have incomplete information.

Do you take Sinemet and Rivaroxaban?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously