Singulair and Intron a drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Singulair (montelukast sodium) and Intron a (interferon alfa-2b). Common drug interactions include pain among females and aphonia among males.

The phase IV clinical study analyzes what interactions people have when they take Singulair and Intron a. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Singulair?

Singulair has active ingredients of montelukast sodium. It is often used in asthma. eHealthMe is studying from 129,752 Singulair users. Check the latest studies of Singulair.

What is Intron a?

Intron a has active ingredients of interferon alfa-2b. eHealthMe is studying from 9,320 Intron a users. Check the latest studies of Intron a.

On Jul, 26, 2026

20 people who take Singulair and Intron a together, and have interactions are studied.

Singulair and Intron a drug interactions.

What are the common drug interactions of Singulair and Intron A, by gender? *:

female:

Pain
Abdominal pain
Adverse event
Fatigue (feeling of tiredness)
Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
Gastroenteritis (inflammation of stomach and intestine)
Gastrointestinal hypermotility (over activity of the intestinal tract)
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
Hypersensitivity
Malaise (a feeling of general discomfort or uneasiness)

male:

Aphonia (inability to produce voice)
Asthenia (weakness)
Fatigue (feeling of tiredness)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Hyperthermia (body temperature greatly above normal)
Loss of consciousness
Lung disorder (lung disease)
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Nephrolithiasis (calculi in the kidneys)
Odynophagia (painful swallowing, in the mouth (oropharynx) or oesophagus)

What are the common drug interactions of Singulair and Intron A, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Pain
Pneumonia
Surgery
Injection site erythema (redness at injection site)
Injection site pain
Injection site reaction
Injection site scar

20-29:

n/a

30-39:

Conjunctivitis (pink eye)
Dry eye (lack of adequate tears)
Ocular rosacea (redness, irritation or burning of the eyes)

40-49:

Abdominal pain
Adverse event
Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
Fatigue (feeling of tiredness)
Gastroenteritis (inflammation of stomach and intestine)
Gastrointestinal hypermotility (over activity of the intestinal tract)
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
Hypersensitivity
Malaise (a feeling of general discomfort or uneasiness)
Pain

50-59:

Gingivitis (inflammation of gums)
Menstrual disorder (disease of menstrual cycle)
Hoarseness (changing voice)
Sore throat (pain or irritation of the throat)
Vocal cord paralysis
White blood cell count decreased
Dysphonia (speech disorder attributable to a disorder of phonation)

60+:

Blood magnesium decreased
Hip arthroplasty
Malignant hypertension (a hypertensive emergency is a condition in which elevated blood pressure results in target organ damage)
Constipation
Eye haemorrhage (bleeding in the eye)

What are the existing conditions these people have? *

Urticaria Pigmentosa (skin disease that produces patches of darker skin (lesions) and very bad itching): 4 people, 20.00%
Benign Laryngeal Neoplasm (benign (non-cancerous) tumours of the laryngeal): 3 people, 15.00%
Systemic Mastocytosis (a condition caused by the accumulation of mast cells in more than one part of the body): 2 people, 10.00%
Respiratory Papilloma (benign tumour, as a polyp or wart, of the skin or mucous membrane of respiratory system): 2 people, 10.00%
Renal Cell Carcinoma (a kidney cancer): 2 people, 10.00%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 1 person, 5.00%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 1 person, 5.00%
Coughing Up Blood: 1 person, 5.00%
Cough: 1 person, 5.00%
Beta Haemolytic Streptococcal Infection (infection with streptococcus pyogenes, a beta-haemolytic bacterium cause mild to moderately severe respiratory tract, skin, and soft tissue): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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