Singulair and Migranal drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Singulair (montelukast sodium) and Migranal (dihydroergotamine mesylate). Common drug interactions include fatigue among females.

The phase IV clinical study analyzes what interactions people have when they take Singulair and Migranal. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Singulair?

Singulair has active ingredients of montelukast sodium. It is often used in asthma. eHealthMe is studying from 129,752 Singulair users. Check the latest studies of Singulair.

What is Migranal?

Migranal has active ingredients of dihydroergotamine mesylate. It is often used in migraine. eHealthMe is studying from 560 Migranal users. Check the latest studies of Migranal.

On Jul, 12, 2026

20 people who take Singulair and Migranal together, and have interactions are studied.

Singulair and Migranal drug interactions.

What are the common drug interactions of Singulair and Migranal, by gender? *:

female:

Fatigue (feeling of tiredness)
Dyspnoea (difficult or laboured respiration)
Insomnia (sleeplessness)
Ocular toxicity (damages eye)
Paranasal sinus hypersecretion
Pyrexia (fever)
Retinal dystrophy (progressive weakness and wasting of the retina)
Retinopathy (acute damage to the retina of the eye)
Stress
Vitreous detachment (a condition of the eye in which the vitreous humour separates from the retina)

male:

n/a

What are the common drug interactions of Singulair and Migranal, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Anaphylactic reaction (serious allergic reaction)

20-29:

Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Sinusitis (inflammation of sinus)
Wheezing (a high-pitched whistling sound made while you breath)
Facial pain
Headache (pain in head)
Paranasal sinus hypersecretion
Pyrexia (fever)
Anxiety
Body temperature increased

30-39:

Adjustment disorder
Alopecia (absence of hair from areas of the body)
Anxiety
Attention deficit hyperactivity disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness)
Brain neoplasm (tumour of brain)
Candidiasis (candidiasis or thrush is a fungal infection)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Constipation
Dependent personality disorder
Depression

40-49:

Accidental exposure
Chest discomfort
Chest pain
Latex allergy
Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)

50-59:

n/a

60+:

Cataract (clouding of the lens inside the eye)
Drug ineffective
Scar
Ocular toxicity (damages eye)
Retinal dystrophy (progressive weakness and wasting of the retina)
Retinopathy (acute damage to the retina of the eye)
Vitreous detachment (a condition of the eye in which the vitreous humour separates from the retina)
Blood creatinine increased
Injection site pain
Laryngeal haemorrhage (bleeding from larynx)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 15.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 15.00%
Urinary Tract Infection: 2 people, 10.00%
Irritable Bowel Syndrome: 2 people, 10.00%
Bladder Pain: 2 people, 10.00%
Cystitis Interstitial (unknown cause characterized by bladder pain): 2 people, 10.00%
Food Allergy: 2 people, 10.00%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 2 people, 10.00%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 10.00%
Menopause (end of monthly cycles in women): 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

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