Singulair and Minocin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Singulair (montelukast sodium) and Minocin (minocycline hydrochloride). Common drug interactions include back pain among females and dermatitis among males.
The phase IV clinical study analyzes what interactions people have when they take Singulair and Minocin. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.
What is Singulair?
Singulair has active ingredients of montelukast sodium. It is often used in asthma. eHealthMe is studying from 129,752 Singulair users. Check the latest studies of Singulair.
What is Minocin?
Minocin has active ingredients of minocycline hydrochloride. It is often used in acne. eHealthMe is studying from 2,278 Minocin users. Check the latest studies of Minocin.
38 people who take Singulair and Minocin together, and have interactions are studied.

What are the common drug interactions of Singulair and Minocin, by gender? *:
female:
- Back pain
- Chest pain
- Coagulopathy (blood's ability to clot is impaired)
- Constipation
- Death
- Decreased appetite
- Fall
- Flatulence (flatus expelled through the anus)
- Fluid retention (an abnormal accumulation of fluid in the blood)
- Frostbite (damage is caused to skin and other tissues due to freezing)
male:
- Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Cardioactive drug level increased
- Carotidynia (unilateral (one-sided) tenderness of the carotid artery)
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Dizziness
- Dysphagia (a condition in which swallowing is difficult or painful)
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
What are the common drug interactions of Singulair and Minocin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Bone cyst
- Bone disorder
- Gastrointestinal pain
- Hypersensitivity
- Sinusitis (inflammation of sinus)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Therapeutic response delayed (late preventive response)
20-29:
- Coagulopathy (blood's ability to clot is impaired)
- Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
- Depression
- Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
- Inflammatory bowel disease
- International normalised ratio increased
- Activated partial thromboplastin time prolonged
30-39:
n/a
40-49:
- Frostbite (damage is caused to skin and other tissues due to freezing)
- Loss of consciousness
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
50-59:
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- Hypotension (abnormally low blood pressure)
- Pain
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Arthralgia (joint pain)
- Asthenia (weakness)
- Attention deficit/hyperactivity disorder
- Autonomic neuropathy (malfunction of the autonomic nervous system (ans))
60+:
- Hospitalisation
- Nasopharyngitis (inflammation of the nasopharynx)
- Headache (pain in head)
- Hot flush (sudden feelings of heat)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Peripheral swelling
- Pruritus (severe itching of the skin)
- Renal failure (kidney dysfunction)
- Renal injury (kidney injury)
- Renal tubular necrosis (death of kidney tubules)
What are the existing conditions these people have? *
- Hyperkalemia (damage to or disease of the kidney): 5 people, 13.16%
- Pulmonary Hypertension (increase in blood pressure in the lung artery): 4 people, 10.53%
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 10.53%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 10.53%
- Drowsiness: 4 people, 10.53%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 10.53%
- Pain: 3 people, 7.89%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 7.89%
- Allergic Rhinitis: 3 people, 7.89%
- Rosacea (a skin condition that causes facial redness): 2 people, 5.26%
* Approximation only. Some reports may have incomplete information.
Do you take Singulair and Minocin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Singulair and Minocin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Singulair:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Minocin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Singulair and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Minocin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Das S, Mondal S, Dey JK, Bandyopadhyay S, Saha I, Tripathi SK, "A case of montelukast induced hypercholesterolemia, severe hypertriglyceridemia and pancreatitis", Journal of Young Pharmacists, 2013 Jun .
- Das S, Mondal S, Dey JK, Bandyopadhyay S, Saha I, Tripathi SK, "A case of montelukast induced hypercholesterolemia, severe hypertriglyceridemia and pancreatitis", Journal of Young Pharmacists, 2013 Jun .
How the study uses the data?
The study uses data from the FDA. It is based on montelukast sodium and minocycline hydrochloride (the active ingredients of Singulair and Minocin, respectively), and Singulair and Minocin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Could Gaviscon cause Myoclonic Jerks? - a second ago
- Affective Disorder and Breast Discharge - 14 seconds ago
- Drug interactions of Abraxane and Folate - 17 seconds ago
- Drug interactions of Gentamicin and Klor-Con - 19 seconds ago
- Drug interactions of Genvoya and Gemfibrozil - 23 seconds ago
- Drug interactions of Xylitol and Pantoprazole - 25 seconds ago
- Drug interactions of Abilify and Lactobacillus - 31 seconds ago
- Drug interactions of Inocor and Trasylol - 34 seconds ago
- Could Toprol-Xl cause Pulmonary Congestion? - 40 seconds ago
- Could Docetaxel cause Bronchitis? - 41 seconds ago