Singulair and Motegrity drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Singulair (montelukast sodium) and Motegrity (prucalopride succinate). Common drug interactions include constipation among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Singulair and Motegrity. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Singulair?

Singulair has active ingredients of montelukast sodium. It is often used in asthma. eHealthMe is studying from 129,752 Singulair users. Check the latest studies of Singulair.

What is Motegrity?

Motegrity has active ingredients of prucalopride succinate. eHealthMe is studying from 1,380 Motegrity users. Check the latest studies of Motegrity.

On Aug, 02, 2026

39 people who take Singulair and Motegrity together, and have interactions are studied.

Singulair and Motegrity drug interactions.

What are the common drug interactions of Singulair and Motegrity, by gender? *:

female:

Constipation
Migraine (headache)
Pruritus (severe itching of the skin)
Urticaria (rash of round, red welts on the skin that itch intensely)
Drug ineffective
Suicidal ideation
Anxiety
Arthralgia (joint pain)
Dehydration (dryness resulting from the removal of water)
Hypertension (high blood pressure)

male:

Dyspnoea (difficult or laboured respiration)
Hemiplegia (paralysis of one side of the body)
Hyperhidrosis (abnormally increased sweating)
Sputum discoloured
Swollen tongue (swelling of tongue)
Urticaria (rash of round, red welts on the skin that itch intensely)

What are the common drug interactions of Singulair and Motegrity, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Foot fracture
Hypoaesthesia (reduced sense of touch or sensation)
Ligament sprain (ligament stretched)
Lyme disease (a bacterial infection that is spread to humans by infected ticks)
Neuroma (tumour of nerve tissue)
Pain
Pain in extremity
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pruritus (severe itching of the skin)
Urticaria (rash of round, red welts on the skin that itch intensely)

30-39:

Age-related macular degeneration
Anxiety
Depression
Fall
Hand fracture
Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest)
Multiple injuries
Retinal degeneration (death of the cells of the retina)
Retinal tear
Vitreous detachment (a condition of the eye in which the vitreous humour separates from the retina)

40-49:

Headache (pain in head)
Pruritus (severe itching of the skin)
Urticaria (rash of round, red welts on the skin that itch intensely)
Chest discomfort
Cough
Dyspnoea (difficult or laboured respiration)
Rash

50-59:

Alopecia (absence of hair from areas of the body)
Drug ineffective
Infection
Anxiety
Deafness
Immunisation reaction
Injection site swelling
Stress
Vertigo
Hyperhidrosis (abnormally increased sweating)

60+:

Muscle spasms (muscle contraction)
Suicidal behaviour
Suicidal ideation
Tearfulness (excess tearing)
Dyspnoea (difficult or laboured respiration)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Pneumonia
Sputum discoloured

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 5 people, 12.82%
Constipation: 4 people, 10.26%
Primary Immunodeficiency Syndrome: 3 people, 7.69%
Dermatomyositis (inflammation of the skin and underlying muscle tissue, typically occurring as an autoimmune condition or associated with internal cancer): 3 people, 7.69%
Pain: 2 people, 5.13%
Nausea And Vomiting: 2 people, 5.13%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 5.13%
Migraine (headache): 2 people, 5.13%
Irritable Bowel Syndrome: 2 people, 5.13%
Immunodeficiency: 2 people, 5.13%

* Approximation only. Some reports may have incomplete information.

Do you take Singulair and Motegrity?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously