Sirolimus and Remicade drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sirolimus (sirolimus) and Remicade (infliximab). Common drug interactions include transplant rejection among females and pericarditis among males.

The phase IV clinical study analyzes what interactions people have when they take Sirolimus and Remicade. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Sirolimus?

Sirolimus has active ingredients of sirolimus. eHealthMe is studying from 11,823 Sirolimus users. Check the latest studies of Sirolimus.

What is Remicade?

Remicade has active ingredients of infliximab. It is often used in crohn's disease. eHealthMe is studying from 224,011 Remicade users. Check the latest studies of Remicade.

On Jul, 10, 2026

19 people who take Sirolimus and Remicade together, and have interactions are studied.

Sirolimus and Remicade drug interactions.

What are the common drug interactions of Sirolimus and Remicade, by gender? *:

female:

Transplant rejection (a transplant material is not worked)
Dehydration (dryness resulting from the removal of water)
Drug ineffective
Escherichia sepsis (bacterial infection by escherichia coli)
Hyperchloraemia (an excess of chlorides in the blood)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Inflammatory bowel disease
Klebsiella sepsis (klebsiella causes a potentially fatal whole-body inflammation)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Renal impairment (severely reduced kidney function)

male:

Pericarditis (inflammation of the pericardium)
Breast pain
Cardiac flutter (abnormal heart rhythm)
Ankylosing spondylitis (type of arthritis affecting the spine)
Arthralgia (joint pain)
Cytomegalovirus infection
Extraskeletal ossification (formation of bone tissue outside of bone tissue)
Fatigue (feeling of tiredness)
Fibrous dysplasia of bone (an abnormal bone growth where normal bone is replaced with fibrous bone tissue)
Gastroenteritis norovirus (inflammation of stomach and intestine caused by norovirus infection)

What are the common drug interactions of Sirolimus and Remicade, by age (0-1 to 60+)? *:

0-1:

Gastroenteritis norovirus (inflammation of stomach and intestine caused by norovirus infection)

2-9:

Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Inflammatory bowel disease
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)

10-19:

Gastrointestinal stoma complication (complication of an opening surgically made in digestive tract)
Pneumonia

20-29:

Dehydration (dryness resulting from the removal of water)
Escherichia sepsis (bacterial infection by escherichia coli)
Hyperchloraemia (an excess of chlorides in the blood)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Klebsiella sepsis (klebsiella causes a potentially fatal whole-body inflammation)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Renal impairment (severely reduced kidney function)
Transplant rejection (a transplant material is not worked)
Diarrhoea
Diffuse alveolar damage (common manifestation of drug-induced lung injury)

30-39:

Pericarditis (inflammation of the pericardium)
Breast pain
Duodenal fistula
Haematoma infection (infection with collection of blood outside the blood vessels)
Peripancreatic fluid collection
Portal vein thrombosis (venous thrombosis affecting the hepatic portal vein)
Pyelonephritis acute (sudden inflammation of kidney caused by bacteria)
Septic shock (shock due to blood infection)
Streptococcal sepsis (whole body inflammation by streptococcal)
Adverse event

40-49:

Acne (skin problems that cause pimples)
Alopecia (absence of hair from areas of the body)
Drug ineffective
Hepatic enzyme increased
Ovarian cyst (fluid filled sac of the ovary)
Pain
Sleep disorder due to general medical condition, insomnia type (a conditions that prevent a person from getting restful sleep due to mental condition of not getting sleep)
Stress
Transplant rejection (a transplant material is not worked)

50-59:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardiac flutter (abnormal heart rhythm)

60+:

Ankylosing spondylitis (type of arthritis affecting the spine)
Arthralgia (joint pain)
Kyphosis (a condition of over-curvature of the thoracic vertebrae (upper back))
Ligament sprain (ligament stretched)
Neck pain
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Red blood cell count decreased
Skin plaque (red, scaly patches to appear on the skin)
Spinal osteoarthritis (joint cartilage loss in spine)
Spondylolisthesis (displacement of a vertebra or the vertebral column in relation to the vertebrae below)

What are the existing conditions these people have? *

Inflammatory Bowel Disease: 7 people, 36.84%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 15.79%
Stress And Anxiety: 2 people, 10.53%
Immunodeficiency Disorders: 2 people, 10.53%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 2 people, 10.53%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 5.26%
Renal Disorder (kidney disease): 1 person, 5.26%
High Blood Cholesterol: 1 person, 5.26%
Hidradenitis (chronic disease of a type of sweat gland): 1 person, 5.26%
Heart Rate Irregular: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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