Sitagliptin phosphate and Isosorbide dinitrate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sitagliptin phosphate (sitagliptin phosphate) and Isosorbide dinitrate (isosorbide dinitrate). Common drug interactions include colitis among females and altered state of consciousness among males.

The phase IV clinical study analyzes what interactions people have when they take Sitagliptin phosphate and Isosorbide dinitrate. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Sitagliptin phosphate?

Sitagliptin phosphate has active ingredients of sitagliptin phosphate. eHealthMe is studying from 3,787 Sitagliptin phosphate users. Check the latest studies of Sitagliptin phosphate.

What is Isosorbide dinitrate?

Isosorbide dinitrate has active ingredients of isosorbide dinitrate. It is often used in angina. eHealthMe is studying from 13,180 Isosorbide dinitrate users. Check the latest studies of Isosorbide dinitrate.

On Jul, 17, 2026

31 people who take Sitagliptin phosphate and Isosorbide dinitrate together, and have interactions are studied.

Sitagliptin phosphate and Isosorbide dinitrate drug interactions.

What are the common drug interactions of Sitagliptin Phosphate and Isosorbide Dinitrate, by gender? *:

female:

Colitis (inflammation of colon)
Leukopenia (less number of white blood cells in blood)
Thrombocytopenia (decrease of platelets in blood)
Asthma
Bacteraemia (presence of bacteria in the blood)
Cardiac failure
Cellulitis (infection under the skin)
Colon adenoma (non cancerous epithelial colon tumour having a glandular origin and structure)
Dyspnoea (difficult or laboured respiration)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)

male:

Altered state of consciousness (altered state of mind)
Hypotension (abnormally low blood pressure)
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
Cardiac failure acute
Cardiac failure congestive
Cardiomegaly (increased size of heart than normal)
Cataract (clouding of the lens inside the eye)
Chronic kidney disease
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Disease progression

What are the common drug interactions of Sitagliptin Phosphate and Isosorbide Dinitrate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)
Throat cancer

50-59:

Alanine aminotransferase increased
Aortic valve incompetence
Aspartate aminotransferase increased
Blood glucose increased
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
Cardiac failure congestive
Cardiomegaly (increased size of heart than normal)
Cataract (clouding of the lens inside the eye)
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)

60+:

Altered state of consciousness (altered state of mind)
Thrombocytopenia (decrease of platelets in blood)
Hepatosplenic candidiasis (fungal infection in liver and spleen)
Hypotension (abnormally low blood pressure)
Pancreatic mass
Blood fibrinogen decreased
Blood pressure decreased
Bradycardia (abnormally slow heart action)
Cardiac failure acute
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

What are the existing conditions these people have? *

Pain: 6 people, 19.35%
Multiple Myeloma (cancer of the plasma cells): 5 people, 16.13%
High Blood Pressure: 5 people, 16.13%
Type 2 Diabetes: 4 people, 12.90%
Insomnia (sleeplessness): 4 people, 12.90%
Chest Pain: 4 people, 12.90%
Diabetes: 3 people, 9.68%
Asthma: 3 people, 9.68%
Phantom Pain: 2 people, 6.45%
Pain In Extremity: 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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