Sivextro and Bactrim drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sivextro (tedizolid phosphate) and Bactrim (sulfamethoxazole; trimethoprim). Common drug interactions include hospitalisation among females and back pain among males.

The phase IV clinical study analyzes what interactions people have when they take Sivextro and Bactrim. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Sivextro?

Sivextro has active ingredients of tedizolid phosphate. eHealthMe is studying from 586 Sivextro users. Check the latest studies of Sivextro.

What is Bactrim?

Bactrim has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 89,117 Bactrim users. Check the latest studies of Bactrim.

On Jul, 11, 2026

12 people who take Sivextro and Bactrim together, and have interactions are studied.

What are the common drug interactions of Sivextro and Bactrim, by gender? *:

female:

Hospitalisation
Anxiety
Cystic fibrosis (disease of the secretary glands)
Depression
Dizziness
Dyspnoea (difficult or laboured respiration)
Rash

male:

Back pain
Cellulitis (infection under the skin)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Bursitis infective (the bursa can become infected, this is called infected bursitis)
Cerumen impaction
Chronic kidney disease
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Concussion (short loss of normal brain function in response to a head injury)
Conjunctivitis bacterial (infection of conjunctiva by bacteria)
Cough

What are the common drug interactions of Sivextro and Bactrim, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Hospitalisation

10-19:

Neutropenia (an abnormally low number of neutrophils)

20-29:

Hospitalisation

30-39:

n/a

40-49:

Diabetic foot
Diabetic mononeuropathy (only one nerve is damaged- associated with diabetes)
Erythema (redness of the skin)
Limb injury
Localised infection (infection at the single location)
Muscle necrosis (muscle cell damage)
Nail dystrophy (bed formation of nail)
Osteomyelitis (infection of bone)
Pain in extremity
Peripheral nerve lesion

50-59:

n/a

60+:

Back pain
Cellulitis (infection under the skin)
Cerumen impaction
Chronic kidney disease
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Concussion (short loss of normal brain function in response to a head injury)
Conjunctivitis bacterial (infection of conjunctiva by bacteria)
Cough
Dyspnoea (difficult or laboured respiration)
Emotional distress

What are the existing conditions these people have? *

Cystic Fibrosis (disease of the secretary glands): 3 people, 25.00%
Staphylococcal Infection (an infection with staphylococcus bacteria): 2 people, 16.67%
Staphylococcal Abscess (pus formation due to staphylococcal bacteria): 1 person, 8.33%
Post Procedural Infection: 1 person, 8.33%
Osteoporosis (bones weak and more likely to break): 1 person, 8.33%
Infection: 1 person, 8.33%
Hiv Infection: 1 person, 8.33%
Diarrhea: 1 person, 8.33%
Device Related Infection: 1 person, 8.33%
Constipation: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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