Skyrizi and Clopra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Skyrizi (risankizumab-rzaa) and Clopra (metoclopramide hydrochloride). Common drug interactions include dry mouth among females and brain oedema among males.

The phase IV clinical study analyzes what interactions people have when they take Skyrizi and Clopra. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Skyrizi?

Skyrizi has active ingredients of risankizumab-rzaa. eHealthMe is studying from 45,385 Skyrizi users. Check the latest studies of Skyrizi.

What is Clopra?

Clopra has active ingredients of metoclopramide hydrochloride. eHealthMe is studying from 81,430 Clopra users. Check the latest studies of Clopra.

On Jun, 17, 2026

13 people who take Skyrizi and Clopra together, and have interactions are studied.

What are the common drug interactions of Skyrizi and Clopra, by gender? *:

female:

Dry mouth
Asthenia (weakness)
Chest discomfort
Decreased appetite
Gout (uric acid crystals building up in the body)
Headache (pain in head)
Hypersensitivity
Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
Oxygen saturation decreased
Pneumonia

male:

Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Psoriasis (immune-mediated disease that affects the skin)
Ulcer
Dehydration (dryness resulting from the removal of water)
Dysphagia (a condition in which swallowing is difficult or painful)
Fall
Haematemesis (vomiting of blood)
Head injury
Hypophagia (reduced food intake)

What are the common drug interactions of Skyrizi and Clopra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Migraine (headache)

50-59:

Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)

60+:

Dry mouth
Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
Pharyngeal lesion
Proctalgia (pain in the rectum)
Pyrexia (fever)
Secretion discharge
Urinary tract infection
Fall
Head injury
Abdominal pain

What are the existing conditions these people have? *

Psoriasis (immune-mediated disease that affects the skin): 10 people, 76.92%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 15.38%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 7.69%
Pain: 1 person, 7.69%
Neuralgia (pain in one or more nerves): 1 person, 7.69%
Indigestion: 1 person, 7.69%
Hypersensitivity: 1 person, 7.69%
High Blood Pressure: 1 person, 7.69%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.69%
Diarrhea: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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