Sodium bicarbonate and Nitro-dur drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sodium bicarbonate (sodium bicarbonate) and Nitro-dur (nitroglycerin). Common drug interactions include blood pressure fluctuation among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Sodium bicarbonate and Nitro-dur. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Sodium bicarbonate?

Sodium bicarbonate has active ingredients of sodium bicarbonate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 27,283 Sodium bicarbonate users. Check the latest studies of Sodium bicarbonate.

What is Nitro-dur?

Nitro-dur has active ingredients of nitroglycerin. eHealthMe is studying from 2,414 Nitro-dur users. Check the latest studies of Nitro-dur.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

18 people who take Sodium bicarbonate and Nitro-dur together, and have interactions are studied.

Sodium bicarbonate and Nitro-dur drug interactions.

What are the common drug interactions of Sodium Bicarbonate and Nitro-Dur, by gender? *:

female:

Blood pressure fluctuation
Cardiac failure
Chest pain
Dry eye (lack of adequate tears)
Eye irritation
Eye pain
Fluid retention (an abnormal accumulation of fluid in the blood)
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
General physical condition
Malaise (a feeling of general discomfort or uneasiness)

male:

Cardiac failure congestive
Peripheral ischaemia (impaired circulation to an extremity)
Cytomegalovirus infection
Death
Dehydration (dryness resulting from the removal of water)
Haemorrhage (bleeding)
Hypotension (abnormally low blood pressure)
Muscle atrophy (a decrease in the mass of the muscle)
Oedema peripheral (superficial swelling)
Pallor

What are the common drug interactions of Sodium Bicarbonate and Nitro-Dur, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Arterial occlusion (blockage of a blood vessel, usually with a clot)
Cardiac failure congestive
Cytomegalovirus infection
Pelvic mass
Peripheral ischaemia (impaired circulation to an extremity)
Renal abscess (pus in kidney)
Renal artery thrombosis (blood clot in renal artery)
Renal infarct (kidney damage due to lack of blood supply)
Staphylococcal abscess (pus formation due to staphylococcal bacteria)
Thromboembolism (obstruction of artery by blood clot)

50-59:

n/a

60+:

Chest pain
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Dizziness
Haemorrhage (bleeding)
Hypotension (abnormally low blood pressure)
Palpitations (feelings or sensations that your heart is pounding or racing)
Pneumonia fungal
Post procedural complication
Pruritus (severe itching of the skin)
Pyrexia (fever)

What are the existing conditions these people have? *

Hyperkalemia (damage to or disease of the kidney): 5 people, 27.78%
Neurotrophic Keratopathy (decreased corneal sensitivity and poor corneal healing): 2 people, 11.11%
Hyperparathyroidism Secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary): 2 people, 11.11%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 5.56%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 5.56%
Multiple Myeloma (cancer of the plasma cells): 1 person, 5.56%
Migraine (headache): 1 person, 5.56%
Eye Disorder: 1 person, 5.56%
Diarrhea: 1 person, 5.56%
Chest Pain: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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