Sodium bicarbonate and Tolterodine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sodium bicarbonate (sodium bicarbonate) and Tolterodine (tolterodine tartrate). Common drug interactions include vomiting among females and blood urea increased among males.

The phase IV clinical study analyzes what interactions people have when they take Sodium bicarbonate and Tolterodine. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Sodium bicarbonate?

Sodium bicarbonate has active ingredients of sodium bicarbonate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 27,283 Sodium bicarbonate users. Check the latest studies of Sodium bicarbonate.

What is Tolterodine?

Tolterodine has active ingredients of tolterodine tartrate. It is often used in urge incontinence. eHealthMe is studying from 8,156 Tolterodine users. Check the latest studies of Tolterodine.

On Jul, 11, 2026

42 people who take Sodium bicarbonate and Tolterodine together, and have interactions are studied.

Sodium bicarbonate and Tolterodine drug interactions.

What are the common drug interactions of Sodium Bicarbonate and Tolterodine, by gender? *:

female:

Vomiting
Vulvovaginal dryness
Vulvovaginal pain
Vulvovaginal pruritus (vulvovaginal severe itching)
Urine output decreased
Complications of transplanted kidney
Anxiety
Anaemia (lack of blood)
Constipation
Hyperuricaemia (level of uric acid in the blood that is abnormally high)

male:

Blood urea increased
Low density lipoprotein increased (cholesterol increased in blood)
Chills (felling of cold)
Cough
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Haematochezia (passage of stools containing blood)
Proctalgia (pain in the rectum)
Haemoglobin decreased
Lymphocyte count decreased

What are the common drug interactions of Sodium Bicarbonate and Tolterodine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Blood creatinine increased
Blood glucose increased
Blood urine present
Cytomegalovirus infection
Haemoglobin decreased
Lymphocyte count decreased
Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
Platelet count decreased
White blood cell count increased

20-29:

Kidney transplant rejection
Ureteric stenosis (abnormal narrowing or contraction of a duct or canal)
Hydronephrosis (water inside the kidney)
Complications of transplanted kidney
Urine output decreased

30-39:

Blood urea increased
Low density lipoprotein increased (cholesterol increased in blood)
Red blood cells urine positive
White blood cell count decreased
Diarrhoea
Blood creatinine increased
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Anal abscess
Anal fissure

40-49:

n/a

50-59:

Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)

60+:

Mobility decreased (ability to move is reduced)
Plasma cell myeloma (cancer that begins in plasma cells)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Renal failure acute (rapid kidney dysfunction)
Blood pressure decreased
Chest pain
Constipation
Death
Electrocardiogram qt prolonged
Hypertension (high blood pressure)

What are the existing conditions these people have? *

High Blood Pressure: 28 people, 66.67%
Constipation: 17 people, 40.48%
Urination - Excessive Volume: 17 people, 40.48%
Nausea And Vomiting: 16 people, 38.10%
Blood Glucose Increased: 15 people, 35.71%
Anaesthesia: 15 people, 35.71%
Diarrhea: 14 people, 33.33%
Pain: 11 people, 26.19%
Infection: 10 people, 23.81%
Inflammation: 9 people, 21.43%

* Approximation only. Some reports may have incomplete information.

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