Sodium bicarbonate and Zyvox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sodium bicarbonate (sodium bicarbonate) and Zyvox (linezolid). Common drug interactions include renal failure among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Sodium bicarbonate and Zyvox. It is created by eHealthMe based on reports of 60 people who take the same drugs from the FDA, and is updated regularly.

What is Sodium bicarbonate?

Sodium bicarbonate has active ingredients of sodium bicarbonate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 27,283 Sodium bicarbonate users. Check the latest studies of Sodium bicarbonate.

What is Zyvox?

Zyvox has active ingredients of linezolid. It is often used in mrsa infection. eHealthMe is studying from 9,399 Zyvox users. Check the latest studies of Zyvox.

On Jul, 20, 2026

60 people who take Sodium bicarbonate and Zyvox together, and have interactions are studied.

Sodium bicarbonate and Zyvox drug interactions.

What are the common drug interactions of Sodium Bicarbonate and Zyvox, by gender? *:

female:

Renal failure (kidney dysfunction)
Unresponsive to stimuli
Renal failure acute (rapid kidney dysfunction)
Vomiting
Cardiac arrest
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Renal tubular necrosis (death of kidney tubules)
Respiratory failure (inadequate gas exchange by the respiratory system)
Septic shock (shock due to blood infection)
Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)

male:

Anaemia (lack of blood)
Diarrhoea
Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Pyrexia (fever)
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Pancreatitis (inflammation of pancreas)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)

What are the common drug interactions of Sodium Bicarbonate and Zyvox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Acinetobacter infection (infection by group of bacteria commonly found in soil and water)
Diarrhoea
Diarrhoea haemorrhagic (bloody diarrhoea)
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Haematoma (collection of blood outside the blood vessels)
Pleural effusion (water on the lungs)
Pyrexia (fever)
Septic shock (shock due to blood infection)
Tooth abscess (pus formation in tooth)
Urine output decreased

10-19:

n/a

20-29:

Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Chest pain
Dyspnoea (difficult or laboured respiration)
Hypoaesthesia (reduced sense of touch or sensation)
Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)
Pruritus (severe itching of the skin)

30-39:

Abdominal discomfort
Anaemia (lack of blood)
Blood glucose increased
Blood urea increased
Diarrhoea
Haemoglobin decreased
Hyperuricaemia (level of uric acid in the blood that is abnormally high)
Incision site pain
Lymphocyte count decreased
Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)

40-49:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Lactic acidosis (low ph in body tissues)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Altered state of consciousness (altered state of mind)
Muscular weakness (muscle weakness)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Abscess (pus)
Anorectal infection
Blood creatinine increased
Cerebral atrophy (decrement in size of brain)

50-59:

Hypovolaemic shock (shock caused by severe blood or fluid loss)
Insomnia (sleeplessness)
International normalised ratio increased
Mouth ulceration (mouth ulcers)
Nausea (feeling of having an urge to vomit)
Nephrogenic anaemia (anaemia due to kidney disease)
Neutropenia (an abnormally low number of neutrophils)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)

60+:

Sepsis (a severe blood infection that can lead to organ failure and death)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Diarrhoea
Nephritis interstitial (a kidney condition characterized by swelling in between the kidney tubules)
Palpitations (feelings or sensations that your heart is pounding or racing)
Renal failure (kidney dysfunction)
Respiratory alkalosis (elevated blood ph due to excess breathing)
Respiratory failure (inadequate gas exchange by the respiratory system)

What are the existing conditions these people have? *

High Blood Pressure: 16 people, 26.67%
Infection: 16 people, 26.67%
Pain: 15 people, 25.00%
Hypotension (abnormally low blood pressure): 12 people, 20.00%
Nausea And Vomiting: 10 people, 16.67%
Nausea (feeling of having an urge to vomit): 9 people, 15.00%
Productive Cough: 8 people, 13.33%
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low): 6 people, 10.00%
Anaemia (lack of blood): 6 people, 10.00%
Constipation: 6 people, 10.00%

* Approximation only. Some reports may have incomplete information.

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