Sodium thiosulfate and Furosemide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sodium thiosulfate (sodium thiosulfate) and Furosemide (furosemide). Common drug interactions include gait disturbance among females and blood potassium decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Sodium thiosulfate and Furosemide. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Sodium thiosulfate?

Sodium thiosulfate has active ingredients of sodium thiosulfate. eHealthMe is studying from 427 Sodium thiosulfate users. Check the latest studies of Sodium thiosulfate.

What is Furosemide?

Furosemide has active ingredients of furosemide. It is often used in fluid retention. eHealthMe is studying from 316,095 Furosemide users. Check the latest studies of Furosemide.



On Aug, 03, 2026

15 people who take Sodium thiosulfate and Furosemide together, and have interactions are studied.

Sodium thiosulfate and Furosemide drug interactions.

What are the common drug interactions of Sodium Thiosulfate and Furosemide, by gender? *:

female:

  1. Gait disturbance
  2. Joint contracture (a permanent shortening of a muscle or joint)
  3. Joint range of motion decreased (disease of joint movement)
  4. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  5. Pain
  6. Skin induration (an abnormally hard spot or area on the skin)
  7. Skin tightness
  8. Arthropathy
  9. Dry skin
  10. Mobility decreased (ability to move is reduced)

male:

  1. Blood potassium decreased
  2. Metabolic alkalosis (too much bicarbonate in the blood)
  3. Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)
  4. Drug ineffective
  5. Calcinosis (calcium deposits in any soft tissue)
  6. Enterobacter infection (infection caused by bacteria of the family enterobacteriaceae)
  7. Extravasation (leakage of a fluid)
  8. Nausea (feeling of having an urge to vomit)
  9. Respiratory distress (difficulty in breathing)
  10. Staphylococcal infection (an infection with staphylococcus bacteria)

What are the common drug interactions of Sodium Thiosulfate and Furosemide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Calcinosis (calcium deposits in any soft tissue)
  2. Enterobacter infection (infection caused by bacteria of the family enterobacteriaceae)
  3. Extravasation (leakage of a fluid)
  4. Nausea (feeling of having an urge to vomit)
  5. Respiratory distress (difficulty in breathing)
  6. Staphylococcal infection (an infection with staphylococcus bacteria)
  7. Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Arthralgia (joint pain)
  2. Dysstasia (difficulty in standing)
  3. Gait disturbance
  4. Joint contracture (a permanent shortening of a muscle or joint)
  5. Joint range of motion decreased (disease of joint movement)
  6. Lichenification (thickening and hardening of the skin)
  7. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  8. Ocular icterus (presence of jaundice seen in the sclera of the eye)
  9. Oedema peripheral (superficial swelling)
  10. Pain

60+:

  1. Blood potassium decreased
  2. Metabolic alkalosis (too much bicarbonate in the blood)
  3. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  4. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  5. Oedema (fluid collection in tissue)
  6. Pain
  7. Pruritus generalised (generalized itching)
  8. Rash papular (redness with papule)
  9. Scar
  10. Skin discolouration (change of skin colour)

What are the existing conditions these people have? *

  1. Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood): 5 people, 33.33%
  2. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 33.33%
  3. Hypotension (abnormally low blood pressure): 4 people, 26.67%
  4. Diabetes: 4 people, 26.67%
  5. Iron Deficiency Anaemia: 4 people, 26.67%
  6. Muscle Atrophy (a decrease in the mass of the muscle): 4 people, 26.67%
  7. Muscle Spasms (muscle contraction): 4 people, 26.67%
  8. Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 4 people, 26.67%
  9. Neuropathy Peripheral (surface nerve damage): 4 people, 26.67%
  10. Hyperparathyroidism Secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary): 4 people, 26.67%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Sodium thiosulfate and Furosemide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Sodium thiosulfate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Furosemide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sodium thiosulfate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Furosemide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on sodium thiosulfate and furosemide (the active ingredients of Sodium thiosulfate and Furosemide, respectively), and Sodium thiosulfate and Furosemide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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