Sofosbuvir and Carvedilol drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Sofosbuvir (sofosbuvir) and Carvedilol (carvedilol). Common drug interactions include pneumonia among females and fatigue among males.
The phase IV clinical study analyzes what interactions people have when they take Sofosbuvir and Carvedilol. It is created by eHealthMe based on reports of 97 people who take the same drugs from the FDA, and is updated regularly.
What is Sofosbuvir?
Sofosbuvir has active ingredients of sofosbuvir. eHealthMe is studying from 9,194 Sofosbuvir users. Check the latest studies of Sofosbuvir.
What is Carvedilol?
Carvedilol has active ingredients of carvedilol. It is often used in high blood pressure. eHealthMe is studying from 112,649 Carvedilol users. Check the latest studies of Carvedilol.
97 people who take Sofosbuvir and Carvedilol together, and have interactions are studied.

What are the common drug interactions of Sofosbuvir and Carvedilol, by gender? *:
female:
- Pneumonia
- Back pain
- Constipation
- Anaemia (lack of blood)
- Cardiac failure congestive
- Death
- Epistaxis (bleed from the nose)
- Fatigue (feeling of tiredness)
- Haemoglobin decreased
- Hallucination (an experience involving the perception of something not present)
male:
- Fatigue (feeling of tiredness)
- Anaemia (lack of blood)
- Confusional state
- Depression
- Fat intolerance (inability to use fat by digestive system)
- Frequent bowel movements
- Headache (pain in head)
- Hyperpyrexia (extremely high fever)
- Intestinal infarction (intestinal tissue death)
- Pyrexia (fever)
What are the common drug interactions of Sofosbuvir and Carvedilol, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Renal failure acute (rapid kidney dysfunction)
40-49:
- Arthralgia (joint pain)
- Abscess (pus)
- Anaemia (lack of blood)
- Appetite disorder (abnormal eating habits)
- General physical health deterioration (weak health status)
- Haematochezia (passage of stools containing blood)
- Headache (pain in head)
- Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone)
- Local swelling (swelling at the site of some application of substance or injury)
- Pain in jaw
50-59:
- Depression
- Headache (pain in head)
- Leukopenia (less number of white blood cells in blood)
- Pneumonia
- Abdominal pain lower
- Cardiac failure congestive
- Haemoglobin decreased
- Hallucination (an experience involving the perception of something not present)
- Hepatitis c rna increased
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
60+:
- Pruritus (severe itching of the skin)
- Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
- Hyperpyrexia (extremely high fever)
- Intestinal infarction (intestinal tissue death)
- Drug ineffective
- Hepatic failure (liver failure)
- Hepatitis c
- Chronic kidney disease
- Dyspnoea (difficult or laboured respiration)
- Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
What are the existing conditions these people have? *
- Hepatitis C: 55 people, 56.70%
- Diabetes: 6 people, 6.19%
- Chronic Kidney Disease: 6 people, 6.19%
* Approximation only. Some reports may have incomplete information.
Do you take Sofosbuvir and Carvedilol?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Sofosbuvir (9,194 reports)
- Carvedilol (112,649 reports)
Browse all drug interactions of Sofosbuvir and Carvedilol:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Sofosbuvir:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Carvedilol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Sofosbuvir and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Carvedilol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Barold, S. S., & Upton, S. , "Hyperkalemia Induced by the Sequential Administration of Metoprolol and Carvedilol", Case reports in cardiology, 2018 Jan .
- Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .
- Barold, S. S., & Upton, S. , "Hyperkalemia Induced by the Sequential Administration of Metoprolol and Carvedilol", Case reports in cardiology, 2018 Jan .
- Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on sofosbuvir and carvedilol (the active ingredients of Sofosbuvir and Carvedilol, respectively), and Sofosbuvir and Carvedilol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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