Soliris and Pentamidine isethionate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Soliris (eculizumab) and Pentamidine isethionate (pentamidine isethionate). Common drug interactions include aplastic anaemia among females and acute respiratory failure among males.

The phase IV clinical study analyzes what interactions people have when they take Soliris and Pentamidine isethionate. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Soliris?

Soliris has active ingredients of eculizumab. It is often used in paroxysmal nocturnal hemoglobinuria (pnh). eHealthMe is studying from 58,821 Soliris users. Check the latest studies of Soliris.

What is Pentamidine isethionate?

Pentamidine isethionate has active ingredients of pentamidine isethionate. eHealthMe is studying from 1,967 Pentamidine isethionate users. Check the latest studies of Pentamidine isethionate.

On Jul, 13, 2026

13 people who take Soliris and Pentamidine isethionate together, and have interactions are studied.

Soliris and Pentamidine isethionate drug interactions.

What are the common drug interactions of Soliris and Pentamidine Isethionate, by gender? *:

female:

Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Decreased appetite
Gastric disorder (disease of stomach)
Helicobacter infection (helicobacter pylori (h. pylori) infects stomach)
Nausea (feeling of having an urge to vomit)
Pancreatic disorder
Pancreatitis (inflammation of pancreas)
Abdominal pain
Caecitis (inflammation of the cecum)
Diarrhoea

male:

Acute respiratory failure
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Vomiting
Blood lactate dehydrogenase increased
Haemoglobin decreased
Drug resistance (reduction in effectiveness of a drug)
Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
Oropharyngeal pain
Platelet count decreased
Diarrhoea

What are the common drug interactions of Soliris and Pentamidine Isethionate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Diarrhoea
Hepatic enzyme increased
Nausea (feeling of having an urge to vomit)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Respiratory distress (difficulty in breathing)
Venoocclusive liver disease (small veins in the liver are obstructed)
Vomiting
Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Acute respiratory failure

10-19:

Drug ineffective
Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
Blood lactate dehydrogenase increased
Haemoglobin decreased
Abdominal pain
Caecitis (inflammation of the cecum)
Diarrhoea
Oropharyngeal pain
Platelet count decreased

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Decreased appetite
Gastric disorder (disease of stomach)
Helicobacter infection (helicobacter pylori (h. pylori) infects stomach)
Nausea (feeling of having an urge to vomit)
Pancreatic disorder
Pancreatitis (inflammation of pancreas)

60+:

Blood lactate dehydrogenase increased
Drug resistance (reduction in effectiveness of a drug)
Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)

What are the existing conditions these people have? *

Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 6 people, 46.15%
Cytomegalovirus Infection: 2 people, 15.38%
Sleep Disorder: 1 person, 7.69%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 1 person, 7.69%
Haemolytic Uraemic Syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more): 1 person, 7.69%
Blood Glucose Increased: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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