Solu-cortef and Ancef drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Solu-cortef (hydrocortisone sodium succinate) and Ancef (cefazolin sodium). Common drug interactions include acute respiratory distress syndrome among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Solu-cortef and Ancef. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Solu-cortef?

Solu-cortef has active ingredients of hydrocortisone sodium succinate. eHealthMe is studying from 7,983 Solu-cortef users. Check the latest studies of Solu-cortef.

What is Ancef?

Ancef has active ingredients of cefazolin sodium. eHealthMe is studying from 3,292 Ancef users. Check the latest studies of Ancef.

On Jul, 16, 2026

36 people who take Solu-cortef and Ancef together, and have interactions are studied.

Solu-cortef and Ancef drug interactions.

What are the common drug interactions of Solu-Cortef and Ancef, by gender? *:

female:

Acute respiratory distress syndrome
Acute respiratory failure
Adams-stokes syndrome (sudden attacks of unconsciousness)
Alopecia areata (patchy baldness that typically begins with rapid hair loss)
Alopecia totalis (loss of all head hair)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Atrioventricular block (heart block)
Blood glucose increased
Blood pressure fluctuation

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Stress
Death
Dyspnoea (difficult or laboured respiration)
Oedema peripheral (superficial swelling)
Respiratory failure (inadequate gas exchange by the respiratory system)
Abdominal distension
Anaemia (lack of blood)
Asbestosis (chronic lung disease caused by scarring of lung tissue, which stems from prolonged exposure to asbestos)

What are the common drug interactions of Solu-Cortef and Ancef, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abdominal sepsis (abdominal infection)
Pulmonary embolism (blockage of the main artery of the lung)
Small intestinal obstruction (blockage in small intestine)

20-29:

Abortion (termination of pregnancy)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Injury
Pain
Postoperative thrombosis (formation of a blood clot inside a blood vessel after operative)

30-39:

n/a

40-49:

Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Hypertension (high blood pressure)
Hyperthermia (body temperature greatly above normal)
Oxygen saturation decreased
Psychomotor hyperactivity (feelings of extreme restlessness)
Pulmonary oedema (fluid accumulation in the lungs)
Respiratory distress (difficulty in breathing)
Tachypnoea (a condition of rapid breathing over 20 per minute)

50-59:

Asthenia (weakness)
Diarrhoea
Enterocolonic fistula
Fatigue (feeling of tiredness)
Groin pain
Hair colour changes
Hydrocele
Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
Large intestine perforation (hole in large intestine)
Malaise (a feeling of general discomfort or uneasiness)

60+:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Renal impairment (severely reduced kidney function)
Death
Dyspnoea (difficult or laboured respiration)
Oedema peripheral (superficial swelling)
Pleural effusion (water on the lungs)
Respiratory failure (inadequate gas exchange by the respiratory system)
Abdominal distension
Anaemia (lack of blood)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 13.89%
Pain: 5 people, 13.89%
Hypersensitivity: 5 people, 13.89%
Rickets (softening of bones): 5 people, 13.89%
Muscle Spasms (muscle contraction): 5 people, 13.89%
High Blood Pressure: 4 people, 11.11%
Hyperglycemia (high blood sugar): 4 people, 11.11%
Diarrhea: 4 people, 11.11%
Nausea (feeling of having an urge to vomit): 4 people, 11.11%
Urinary Tract Infection: 4 people, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Solu-cortef and Ancef?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously