Solu-cortef and Apixaban drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Solu-cortef (hydrocortisone sodium succinate) and Apixaban (apixaban). Common drug interactions include abdominal distension among females and acute myeloid leukaemia recurrent among males.

The phase IV clinical study analyzes what interactions people have when they take Solu-cortef and Apixaban. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Solu-cortef?

Solu-cortef has active ingredients of hydrocortisone sodium succinate. eHealthMe is studying from 7,983 Solu-cortef users. Check the latest studies of Solu-cortef.

What is Apixaban?

Apixaban has active ingredients of apixaban. It is often used in blood clots. eHealthMe is studying from 60,351 Apixaban users. Check the latest studies of Apixaban.

On Jul, 15, 2026

12 people who take Solu-cortef and Apixaban together, and have interactions are studied.

Solu-cortef and Apixaban drug interactions.

What are the common drug interactions of Solu-Cortef and Apixaban, by gender? *:

female:

Abdominal distension
Blood pressure fluctuation
Blood pressure increased
Body temperature decreased
Dyspnoea (difficult or laboured respiration)
Lower respiratory tract infection
Pneumonia
Weight increased
Wheezing (a high-pitched whistling sound made while you breath)
Cough

male:

Acute myeloid leukaemia recurrent (acute cancer in which the bone marrow makes abnormal myeloblast- recurrent)
Renal impairment (severely reduced kidney function)
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Embolism venous (embolus may pass into the arterial system)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Troponin increased

What are the common drug interactions of Solu-Cortef and Apixaban, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Heart rate decreased
Abdominal distension
Weight increased
Wheezing (a high-pitched whistling sound made while you breath)
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Embolism venous (embolus may pass into the arterial system)
Cough
Myalgia (muscle pain)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)

What are the existing conditions these people have? *

Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 6 people, 50.00%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 4 people, 33.33%
Tumor Lysis Syndrome: 1 person, 8.33%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1 person, 8.33%
Diffuse Large B-Cell Lymphoma Refractory (cancer of b cells, a type of white blood cell-relapsed): 1 person, 8.33%
Constipation: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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